ArticleJournal of clinical microbiology2004
Molecular diagnosis of human adenoviruses d and e by a phylogeny-based classification method using a partial hexon sequence.
Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Detection of human adenoviruses in influenza-negative patients with respiratory tract infections in Nanning, China.Virology journal · 2023Article
- Potential Diagnostic and Prognostic Biomarkers for Adenovirus Respiratory Infection in Children and Young Adults.Viruses · 2021Review
- A case of severe pneumonia with viremia caused by adenovirus B7 identified by off-label use of a multiplex PCR system.IDCases · 2021Article
- Recent advances in the detection of respiratory virus infection in humans.Journal of medical virology · 2020Review
- Human adenovirus among hospitalized children with respiratory tract infections in Beijing, China, 2017-2018.Virology journal · 2019Article
- Phylogenetic evidence for intratypic recombinant events in a novel human adenovirus C that causes severe acute respiratory infection in children.Scientific reports · 2016Article
- Magnetic Resonance Imaging in Epidemic Adenoviral Keratoconjunctivitis.JAMA ophthalmology · 2015Article
- Article
- Identification of a novel intertypic recombinant species D human adenovirus in a pediatric stem cell transplant recipient.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2014Article
- Isolation of a variant human adenovirus identified based on phylogenetic analysis during an outbreak of acute keratoconjunctivitis in Chennai.The Indian journal of medical research · 2012Article
- Computational analysis of two species C human adenoviruses provides evidence of a novel virus.Journal of clinical microbiology · 2011Article
- Complete genome analysis of a novel intertypic recombinant human adenovirus causing epidemic keratoconjunctivitis in Japan.Journal of clinical microbiology · 2011Article
- Detection of human parechoviruses from clinical stool samples in Aichi, Japan.Journal of clinical microbiology · 2010Article
- Sequential adenovirus infection of type 14 hemorrhagic cystitis and type 35 generalized infection after cord blood transplantation.International journal of hematology · 2009Article
- Epidemic keratoconjunctivitis due to the novel hexon-chimeric-intermediate 22,37/H8 human adenovirus.Journal of clinical microbiology · 2008Article
- Novel human adenovirus causing nosocomial epidemic keratoconjunctivitis.Journal of clinical microbiology · 2008Article
- Quantitative detection and rapid identification of human adenoviruses.Journal of clinical microbiology · 2007Article
- Circulation of incorrectly labeled adenovirus 50 and 51 prototype preparations.Journal of clinical microbiology · 2006Article
- Phylogenetic analysis of the main neutralization and hemagglutination determinants of all human adenovirus prototypes as a basis for molecular classification and taxonomy.Journal of virology · 2005Article
- Comparative sequence analysis of the hexon gene in the entire spectrum of human adenovirus serotypes: phylogenetic, taxonomic, and clinical implications.Journal of virology · 2005Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human adenoviruses (HAdVs) are the major causes of a variety of acute illnesses. Virus isolation and neutralization tests are usually done to identify the causative virus, but these tests are labor-intensive and time-consuming, and standardized antisera are in limited supply. This study investigated a rapid and reliable method of virus identification based on PCR and phylogenetic analysis. The phylogenetic tree constructed by neighbor joining on the basis of the newly determined partial hexon sequences from 33 prototypes of HAdV-D and -E, along with 11 available prototypes of HAdV-A to -C and -F from GenBank, allowed HAdVs to be grouped into six distinct clusters. These clusters correspond closely to the six newly designated species, HAdV-A to -F. The partial hexon sequences of 57 isolates from patients with acute conjunctivitis obtained over 20 years plus those of 44 prototype strains were analyzed. Each isolate formed a monophyletic cluster along with its respective prototype strain, allowing serotype identification. Partial-hexon-based classification appears to be an effective tool for studying the molecular epidemiology of HAdVs.
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