Trial reportWorld journal of gastroenterology2004
Albendazole versus metronidazole treatment of adult giardiasis: An open randomized clinical study.
Trial report in World journal of gastroenterology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Efficacy of 5-nitroimidazoles for the treatment of giardiasis: a systematic review of randomized controlled trials.PLoS neglected tropical diseases · 2014Pooled it
- Drugs for treating giardiasis.The Cochrane database of systematic reviews · 2012Pooled it
- A meta-analysis of the effectiveness of albendazole compared with metronidazole as treatments for infections with Giardia duodenalis.PLoS neglected tropical diseases · 2010Pooled it
- Antiparasitic Activity ofVeterinary sciences · 2026Article
- Diversity and Prevalence of Helminths and Protozoa Among Pregnant Women in Tropical Ecuador: Implications for Chemotherapy.The American journal of tropical medicine and hygiene · 2025Article
- Intestinal Giardiasis Disguised as Ulcerative Colitis.Case reports in gastrointestinal medicine · 2018Article
- Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia.Antimicrobial agents and chemotherapy · 2014Article
- Evaluation of an inhouse rapid ELISA test for detection of giardia in domestic sheep (Ovis aries).Journal of the American Association for Laboratory Animal Science : JAALAS · 2010Article
- The old and new therapeutic approaches to the treatment of giardiasis: where are we?Biologics : targets & therapy · 2009Article
- Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by "amitochondriate" protozoan parasites.Clinical microbiology reviews · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the efficacy and tolerability of albendazole and metranidazole treatment in giardiasis.
methodsThe open comparative randomized trial was carried out prospectively from December 1999 to July 2001 in Duzce City of Turkey. The diagnosis was based on the presence of signs and symptoms compatible with giardiasis including a positive stool examination of giardia cysts or trophozoite. Metranidazole group consisted of 29 patients and was given metranidazole 500 mg, three times a day for 5 d and albendazole group was consisted of 28 patients and was given albendazole 400 mg/d for 5 d.
resultsThere were no significant differences in demographical and therapeutical effects and patient's compliance between both groups. But side effects were seen more in metranidazole group than in albendazole group.
conclusionAlbendazole is as effective as metranidazole in adults' giardiasis. Albendazole has less side effect potentials than metranidazole in the treatment of giardiasis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.