ReviewEndocrine pathology2004
Mechanisms of storage and exocytosis in neuroendocrine tumors.
Review in Endocrine pathology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Neoplastic signatures: Comparative proteomics of canine hepatobiliary neuroendocrine tumors to normal niche tissue.PloS one · 2023Article
- The Rho guanine nucleotide exchange factors Intersectin 1L and β-Pix control calcium-regulated exocytosis in neuroendocrine PC12 cells.Cellular and molecular neurobiology · 2010Review
- Secretory mechanisms and Ca2+ signaling in gametes: similarities to regulated neuroendocrine secretion in somatic cells and involvement in emerging pathologies.Endocrine pathology · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Excitatory and inhibitory neurotransmitters and biogenic amines are important signaling molecules stored by and released from endocrine cells. They are either synthesized or taken up by endocrine cells and subsequently stored in secretory vesicles. Analysis of these storage mechanisms and of the receptors of these paracrine signaling molecules revealed important cross-talk within endocrine glands which add to storage and release of peptide hormones. Components of the exocytosis apparatus are shared by the release of transmitters and hormones. They, as other classical markers, can serve as broad spectrum markers for neuroendocrine tumors. Novel specific markers arise from studies of the synthesis, uptake, and targets of transmitters identified as an additional paracrine signaling system in endocrine systems.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.