ArticleNeuron2004
A voltage-gated calcium-selective channel encoded by a sodium channel-like gene.
Article in Neuron, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed.
- Normal locomotion in zebrafish lacking the sodium channel NaV1.4 suggests that the need for muscle action potentials is not universal.PLoS biology · 2025Article
- Honeybee CaV4 has distinct permeation, inactivation, and pharmacology from homologous NaV channels.The Journal of general physiology · 2024Article
- Electrophysiology of Ctenophore Smooth Muscle.Methods in molecular biology (Clifton, N.J.) · 2024Article
- A governance of ion selectivity based on the occupancy of the "beacon" in one- and four-domain calcium and sodium channels.Channels (Austin, Tex.) · 2023Article
- Cellular and behavioral effects of altered NaV1.2 sodium channel ion permeability in Scn2aK1422E mice.Human molecular genetics · 2022Article
- In silico identification and assessment of insecticide target sites in the genome of the small hive beetle, Aethina tumida.BMC genomics · 2020Article
- Diversity and convergence of mechanisms involved in pyrethroid resistance in the stored grain weevils, Sitophilus spp.Scientific reports · 2018Article
- Eukaryotic Voltage-Gated Sodium Channels: On Their Origins, Asymmetries, Losses, Diversification and Adaptations.Frontiers in physiology · 2018Article
- Voltage-gated sodium channel gene repertoire of lampreys: gene duplications, tissue-specific expression and discovery of a long-lost gene.Proceedings. Biological sciences · 2017Article
- CaThe Journal of physiology · 2017Review
- Molecular Characterization of Voltage-Gated Sodium Channels and Their Relations with Paralytic Shellfish Toxin Bioaccumulation in the Pacific Oyster Crassostrea gigas.Marine drugs · 2017Article
- What makes a sodium channel?The Journal of general physiology · 2016Article
- Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca2+ channel subfamily: CaV4.The Journal of general physiology · 2016Article
- Expression patterns, mutation detection and RNA interference of Rhopalosiphum padi voltage-gated sodium channel genes.Scientific reports · 2016Article
- RNAi-mediated knockdown of the voltage gated sodium ion channel TcNav causes mortality in Tribolium castaneum.Scientific reports · 2016Article
- Cloning and molecular characterization of a putative voltage-gated sodium channel gene in the crayfish.Invertebrate neuroscience : IN · 2016Article
- Physiology and Evolution of Voltage-Gated Calcium Channels in Early Diverging Animal Phyla: Cnidaria, Placozoa, Porifera and Ctenophora.Frontiers in physiology · 2016Article
- Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides.Scientific reports · 2015Article
- Distinct roles of the DmNav and DSC1 channels in the action of DDT and pyrethroids.Neurotoxicology · 2015Article
- An evolutionarily-unique heterodimeric voltage-gated cation channel found in aphids.FEBS letters · 2015Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
BSC1, which was originally identified by its sequence similarity to voltage-gated Na(+) channels, encodes a functional voltage-gated cation channel whose properties differ significantly from Na(+) channels. BSC1 has slower kinetics of activation and inactivation than Na(+) channels, it is more selective for Ba(2+) than for Na(+), it is blocked by Cd(2+), and Na(+) currents through BSC1 are blocked by low concentrations of Ca(2+). All of these properties are more similar to voltage-gated Ca(2+) channels than to voltage-gated Na(+) channels. The selectivity for Ba(2+) is partially due to the presence of a glutamate in the pore-forming region of domain III, since replacing that residue with lysine (normally present in voltage-gated Na(+) channels) makes the channel more selective for Na(+). BSC1 appears to be the prototype of a novel family of invertebrate voltage-dependent cation channels with a close structural and evolutionary relationship to voltage-gated Na(+) and Ca(2+) channels.
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Registered trials
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