ReviewJournal of clinical laboratory analysis2004
A pathologist's perspective on bone marrow aspiration and biopsy: I. Performing a bone marrow examination.
Review in Journal of clinical laboratory analysis, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 120 citations in OpenAlex.
- Pathologic risk-based adjuvant chemotherapy for unilateral retinoblastoma following enucleation.Journal of pediatric hematology/oncology · 2014Trial
- Rapid, Point-of-Care Bone Marrow Aspirate Adequacy Assessment Via Deep Ultraviolet Microscopy.Laboratory investigation; a journal of technical methods and pathology · 2025Article
- Simulation-based Bone Marrow Aspiration and Trephine Biopsy Education for Medical Students: A Non-randomized Controlled Trial.Internal medicine (Tokyo, Japan) · 2025Article
- The Role of [Cancers · 2025Article
- Case Report: Pitfalls in bone marrow evaluation: importance of adequate bone marrow sampling.Frontiers in oncology · 2025Article
- Article
- Factors Affecting Diagnostic Yield of Lesional Bone Biopsy in Hematologic Malignancy Patients.Cardiovascular and interventional radiology · 2024Article
- AMLnet, A deep-learning pipeline for the differential diagnosis of acute myeloid leukemia from bone marrow smears.Journal of hematology & oncology · 2023Article
- Etiological Profiles of Patients With Thrombocytopenia in Central India: A Tertiary Centre Study.Cureus · 2022Article
- Impact of the Process Variables on the Yield of Mesenchymal Stromal Cells from Bone Marrow Aspirate Concentrate.Bioengineering (Basel, Switzerland) · 2022Review
- Educational Case: Diagnostic studies for B-cell acute lymphoblastic leukemia.Academic pathology · 2022Article
- Bone marrow aspiration and biopsy: techniques and practice implications.Skeletal radiology · 2022Review
- Bone Marrow Aspiration and Biopsy in Critical Pediatric Patients: A Pathologist's Perspective.Cureus · 2021Review
- Cell Therapy: Types, Regulation, and Clinical Benefits.Frontiers in medicine · 2021Review
- A Synoptic Reporting System to Monitor Bone Marrow Aspirate and Biopsy Quality.Journal of pathology informatics · 2021Article
- Developing and Preliminary Validating an Automatic Cell Classification System for Bone Marrow Smears: a Pilot Study.Journal of medical systems · 2020Article
- CT-guided bone marrow aspirations and biopsies: retrospective study and comparison with blind procedures.Skeletal radiology · 2020Article
- Label-free hematology analysis using deep-ultraviolet microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- A Rationale for the Use of Clotted Vertebral Bone Marrow to Aid Tissue Regeneration Following Spinal Surgery.Scientific reports · 2020Article
- Professional accountability in a sternal bone marrow aspiration: a forensic case report.The Pan African medical journal · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The bone marrow aspirate and biopsy is an important medical procedure for the diagnosis of hematologic malignancies and other diseases, and for the follow-up evaluation of patients undergoing chemotherapy, bone marrow transplantation, and other forms of medical therapy. During the procedure, liquid bone marrow is aspirated from the posterior iliac crest or sternum with a special needle, smeared on glass microscope slides by one of several techniques, and stained by the Wright-Giemsa or other techniques for micro-scopic examination. The bone marrow core biopsy is obtained from the posterior iliac crest with a Jamshidi or similar needle and processed in the same manner as other surgical specimens. Flow cytometric examination, cytochemical stains, cytogenetic and molecular analysis, and other diagnostic procedures can be performed on bone marrow aspirate material, while sections prepared from the bone marrow biopsy can be stained by the immunoperoxidase or other techniques. The bone marrow procedure can be performed with a minimum of discomfort to the patient if adequate local anesthesia is utilized. Pain, bleeding, and infection are rare complications of the bone marrow procedure performed at the posterior iliac crest, while death from cardiac tamponade has rarely occurred from the sternal bone marrow aspiration. The recent development of bone marrow biopsy needles with specially sharpened cutting edges and core-securing devices has reduced the discomfort of the procedure and improved the quality of the specimens obtained.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.