Evidence map›Paper›PMID 15060021›Full record

ArticleGenome research2004

Integrated and sequence-ordered BAC- and YAC-based physical maps for the rat genome.

Martin Krzywinski, John Wallis, Claudia Gösele, Ian Bosdet, Readman Chiu, Tina Graves, Oliver Hummel, Dan Layman, Carrie Mathewson, Natasja Wye and 46 more

Open access · bronzeAbstract readValidation Study
In one paragraph

Article in Genome research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

56 authors at 7 institutions in 3 countries.

Martin KrzywinskiGenome Sciences Centre, British Columbia Cancer Agency, Vancouver, Canada V5Z 4E6.
John Wallis
Claudia Gösele
Ian Bosdet
Readman Chiu
Tina Graves
Oliver Hummel
Dan Layman
Carrie Mathewson
Natasja Wye
Baoli Zhu
Derek Albracht
Jennifer Asano
Sarah Barber
Mabel Brown-John
Susanna Chan
Steve Chand
Alison Cloutier
Jonathon Davito
Chris Fjell
Tony Gaige
Detlev Ganten
Noreen Girn
Kurtis Guggenheimer
Heinz Himmelbauer
Thomas Kreitler
Stephen Leach
Darlene Lee
Hans Lehrach
Michael Mayo
Kelly Mead
Teika Olson
Pawan Pandoh
Anna-Liisa Prabhu
Heesun Shin
Simone Tänzer
Jason Thompson
Miranda Tsai
Jason Walker
George Yang
Mandeep Sekhon
LaDeana Hillier
Heike Zimdahl
Andre Marziali
Kazutoyo Osoegawa
Shaying Zhao
Asim Siddiqui
Pieter J de Jong
Wes Warren
Elaine Mardis
John D McPherson
Richard Wilson
Norbert Hübner
Steven Jones
Marco Marra
Jacqueline Schein
BC Cancer Agency · CAWashington University in St. Louis · USMax Planck Society · DEMax Delbrück Center · DEUniversity of British Columbia · CAJ. Craig Venter Institute · USNational Institutes of Health · US

Funding

SEQUENCING THE MOUSE GENOMEU01HG002155 · NHGRI · WASHINGTON UNIVERSITY · PI WILSON, RICHARD K. · 1999 to 2004
$41.9M
NHGRI NIH HHS HG01165-06NHGRI NIH HHS U01 HG002155NHGRI NIH HHS U01 HG02155
6 · The paper itself

Abstract

As part of the effort to sequence the genome of Rattus norvegicus, we constructed a physical map comprised of fingerprinted bacterial artificial chromosome (BAC) clones from the CHORI-230 BAC library. These BAC clones provide approximately 13-fold redundant coverage of the genome and have been assembled into 376 fingerprint contigs. A yeast artificial chromosome (YAC) map was also constructed and aligned with the BAC map via fingerprinted BAC and P1 artificial chromosome clones (PACs) sharing interspersed repetitive sequence markers with the YAC-based physical map. We have annotated 95% of the fingerprint map clones in contigs with coordinates on the version 3.1 rat genome sequence assembly, using BAC-end sequences and in silico mapping methods. These coordinates have allowed anchoring 358 of the 376 fingerprint map contigs onto the sequence assembly. Of these, 324 contigs are anchored to rat genome sequences localized to chromosomes, and 34 contigs are anchored to unlocalized portions of the rat sequence assembly. The remaining 18 contigs, containing 54 clones, still require placement. The fingerprint map is a high-resolution integrative data resource that provides genome-ordered associations among BAC, YAC, and PAC clones and the assembled sequence of the rat genome.

Indexed as

GenomeAnimalsAutomationChromosomesChromosomes, Artificial, BacterialChromosomes, Artificial, YeastCloning, MolecularComputational BiologyContig MappingDNA FingerprintingGenetic MarkersPhysical Chromosome MappingPolymerase Chain ReactionRatsSequence Analysis, DNAGenetic Markers

Identifiers

PMID15060021
PMCPMC383324
OpenAlexW1932268077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.