Evidence map›Paper›PMID 15060000›Full record

ArticleGenome research2004

Evolution and comparative genomics of odorant- and pheromone-associated genes in rodents.

Richard D Emes, Scott A Beatson, Chris P Ponting, Leo Goodstadt

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Genome research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 113 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Excreted Steroids in Vertebrate Social Communication.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Review
  7. Review
  8. Article
  9. Article
  10. The genomic basis of vomeronasal-mediated behaviour.Mammalian genome : official journal of the International Mammalian Genome Society · 2014
    Review
  11. Article
  12. Article
  13. Sexual dimorphism in olfactory signaling.Current opinion in neurobiology · 2010
    Review
  14. Article
  15. Article
  16. Article
  17. The animal in the genome: comparative genomics and evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2008
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Richard D EmesMRC Functional Genetics Unit, Department of Human Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, UK.
Scott A Beatson
Chris P Ponting
Leo Goodstadt
Centre for Human Genetics · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemical cues influence a range of behavioral responses in rodents. The involvement of protein odorants and odorant receptors in mediating reproductive behavior, foraging, and predator avoidance suggests that their genes may have been subject to adaptive evolution. We have estimated the consequences of selection on rodent pheromones, their receptors, and olfactory receptors. These families were chosen on the basis of multiple gene duplications since the common ancestor of rat and mouse. For each family, codons were identified that are likely to have been subject to adaptive evolution. The majority of such sites are situated on the solvent-accessible surfaces of putative pheromones and the lumenal portions of their likely receptors. We predict that these contribute to physicochemical and functional diversity within pheromone-receptor interaction sites.

Indexed as

Evolution, MolecularAnimalsComputational BiologyGene DuplicationGenomicsGTP-Binding Protein alpha SubunitsGTP-Binding Protein beta SubunitsGTP-Binding Protein gamma SubunitsHistocompatibility Antigens Class IMiceMultigene FamilyPheromonesRatsReceptors, OdorantReceptors, PheromoneSelection, GeneticGTP-Binding Protein alpha SubunitsGTP-Binding Protein beta SubunitsGTP-Binding Protein gamma SubunitsHistocompatibility Antigens Class IPheromonesReceptors, OdorantReceptors, Pheromone

Identifiers

PMID15060000
PMCPMC383303
OpenAlexW2013920609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.