ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2004
Common sensory inputs and differential excitability of segmentally homologous reticulospinal neurons in the hindbrain.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 70 citations in OpenAlex.
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- Differential energetic profile of signal processing in central vestibular neurons.Frontiers in neurology · 2024Article
- Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish.Communications biology · 2021Article
- Social familiarity improves fast-start escape performance in schooling fish.Communications biology · 2021Article
- Survival and Axonal Outgrowth of the Mauthner Cell Following Spinal Cord Crush Does Not Drive Post-injury Startle Responses.Frontiers in cell and developmental biology · 2021Article
- Removing a single neuron in a vertebrate brain forever abolishes an essential behavior.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Influence of Stimulus Intensity on Multimodal Integration in the Startle Escape System of Goldfish.Frontiers in neural circuits · 2019Article
- Modulation of the zebrafish optokinetic reflex by pharmacologic agents targeting GABANeuroscience letters · 2018Article
- Visual Threat Assessment and Reticulospinal Encoding of Calibrated Responses in Larval Zebrafish.Current biology : CB · 2017Article
- 4-dimensional functional profiling in the convulsant-treated larval zebrafish brain.Scientific reports · 2017Article
- Synaptic vesicle release regulates myelin sheath number of individual oligodendrocytes in vivo.Nature neuroscience · 2015Article
- Functional motifs composed of morphologically homologous neurons repeated in the hindbrain segments.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Recording field potentials from zebrafish larvae during escape responses.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2014Article
- Effective sensory modality activating an escape triggering neuron switches during early development in zebrafish.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Behavioral genetics in larval zebrafish: learning from the young.Developmental neurobiology · 2012Review
- Article
- Regeneration in the era of functional genomics and gene network analysis.The Biological bulletin · 2011Article
- Mapping a sensory-motor network onto a structural and functional ground plan in the hindbrain.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Auditory input to CNS is acquired coincidentally with development of inner ear after formation of functional afferent pathway in zebrafish.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
- Automated identification of neurons in 3D confocal datasets from zebrafish brainstem.Journal of microscopy · 2009Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the hindbrain of zebrafish and goldfish, reticulospinal (RS) neurons are arranged in seven segments, with segmental homologs in adjacent segments. The Mauthner cell (M-cell) in the fourth segment (r4) is known to trigger fast escape behavior. Its serial homologs, MiD2cm in r5 and MiD3cm in r6, are predicted to contribute to this behavior, which can be evoked by head-tap stimuli. However, little is known about their input-output properties. Therefore, we studied afferent projections from the auditory posterior eighth nerve (pVIIIn) and firing properties of MiD2cm and MiD3cm for comparison with the M-cell in adult goldfish. Labeling of RS neurons and the pVIIIn afferents with fluorescent tracers showed that the pVIIIn projected to r4-r6. Tone burst and electrical stimulation of the pVIIIn evoked EPSPs in the M-cell, MiD2cm, and MiD3cm. Stepwise depolarization typically elicited a single spike at the onset in the M-cell but repetitive spiking in MiD2cm and MiD3cm. This atypical property of the M-cell was mediated by dendrotoxin-I (DTX-I)-sensitive voltage-gated potassium channels together with recurrent inhibition, because combined application of DTX-I, strychnine, and bicuculline led to continuous repetitive firing in M-cells. The M-cell but not MiD2cm or MiD3cm expressed Kv1.2, a DTX-I-sensitive potassium channel subunit. Thus, the M-cell and its segmental homologs may sense common auditory information but send different outputs to the spinal circuits to control adaptive escape behavior.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.