ReviewThe Indian journal of medical research2004
Gut microflora & toxic metals: chromium as a model.
Review in The Indian journal of medical research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 77 citations in OpenAlex.
- Oxidative, epigenetic changes and fermentation processes in the intestine of rats fed high-fat diets supplemented with various chromium forms.Scientific reports · 2022Article
- Article
- Enrichment and characterization of an effective hexavalent chromium-reducing microbial community YEM001.Environmental science and pollution research international · 2021Article
- Tibet plateau probiotic mitigates chromate toxicity in mice by alleviating oxidative stress in gut microbiota.Communications biology · 2020Article
- Manganese-induced sex-specific gut microbiome perturbations in C57BL/6 mice.Toxicology and applied pharmacology · 2017Article
- Recent advances in role of chromium and its antioxidant combinations in poultry nutrition: A review.Veterinary world · 2016Review
- Chromium [Cr(VI)] biosorption property of the newly isolated actinobacterial probiont Streptomyces werraensis LD22.3 Biotech · 2015Article
- Chromium exposure among children from an electronic waste recycling town of China.Environmental science and pollution research international · 2015Article
- Exposing to cadmium stress cause profound toxic effect on microbiota of the mice intestinal tract.PloS one · 2014Article
- Ecotoxicology inside the gut: impact of heavy metals on the mouse microbiome.BMC pharmacology & toxicology · 2013Article
- Cr(VI) sorption by free and immobilised chromate-reducing bacterial cells in PVA-alginate matrix: equilibrium isotherms and kinetic studies.Environmental science and pollution research international · 2013Article
- Bioremediation and tolerance of humans to heavy metals through microbial processes: a potential role for probiotics?Applied and environmental microbiology · 2012Article
- Reduction of Chromium-VI by Chromium Resistant Lactobacilli: A Prospective Bacterium for Bioremediation.Toxicology international · 2012Article
- Isolation and Growth Characteristics of Chromium(VI) and Pentachlorophenol Tolerant Bacterial Isolate from Treated Tannery Effluent for its Possible Use in Simultaneous Bioremediation.Indian journal of microbiology · 2011Article
- Quality assessment of treated tannery wastewater with special emphasis on pathogenic E. coli detection through serotyping.Environmental monitoring and assessment · 2008Article
- Arsenic and chromium in canned and non-canned beverages in Nigeria: a potential public health concern.International journal of environmental research and public health · 2007Article
Corrections and comments
- Retraction · 2013-12-01Error by Journal/Publisher ·
- RetractedRetraction.2013
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gastrointestinal tract (GIT) is exposed to various environmental pollutants including metals, that contaminate food and water which may have toxic effects on body. GIT has large amount of microbes that live in symbiosis and help the host in different ways. The resident gut microflora have a significant role to play in detoxification and elimination of the harmful metals from the body. Chromium is a naturally occurring heavy metal found commonly in environment in trivalent (Cr III) and hexavalent (Cr VI) forms. Cr (VI) compounds have been shown to be potent occupational carcinogens. The reduction of Cr (VI) to Cr (III) results in the formation of reactive intermediates that together with oxidative stress and oxidative tissue damage, and a cascade of cellular events including modulation of apoptosis regulatory gene p53 contribute to the cytotoxicity, genotoxicity and carcinogenicity of Cr(VI)-containing compounds. The data discussed here with reference to chromium show that gut microflora have a marked capacity to cope with the increased load of ingested metals and may contribute significantly in the protection against metal toxicity.
Indexed as
Identifiers
15055483W2108471585What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.