ArticlePlant physiology2004
Differential expression of vacuolar H+-ATPase subunit c genes in tissues active in membrane trafficking and their roles in plant growth as revealed by RNAi.
Article in Plant physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 129 citations in OpenAlex.
- Content characteristics and genetic architecture of macronutrient signatures in cottonseed.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- V-ATPases and amino acid catabolism are strongly disturbed in the roots of autophagy mutants in Arabidopsis, impacting water use efficiency and tricarboxylic acid metabolism.The Plant journal : for cell and molecular biology · 2025Article
- Contributions of lignification, tissue arrangement patterns, and cross-sectional area to whole-stem mechanical properties in Arabidopsis thaliana.Journal of plant research · 2024Article
- Creating Climate-Resilient Crops by Increasing Drought, Heat, and Salt Tolerance.Plants (Basel, Switzerland) · 2024Review
- Cell-Type-Specific Length and Cytosolic pH Response of Superficial Cells ofPlants (Basel, Switzerland) · 2022Article
- The Plant V-ATPase.Frontiers in plant science · 2022Review
- Genetic dissection of the soybean dwarf mutantFrontiers in plant science · 2022Article
- Genome-Wide Identification of the Vacuolar HPlants (Basel, Switzerland) · 2020Article
- Article
- Review
- BTB-BACK-TAZ domain protein MdBT2-mediated MdMYB73 ubiquitination negatively regulates malate accumulation and vacuolar acidification in apple.Horticulture research · 2020Article
- Analysis of Interacting Proteins of Aluminum Toxicity Response Factor ALS3 and CAD inInternational journal of molecular sciences · 2019Article
- The V-ATPase subunit A is essential for salt tolerance through participating in vacuolar NaPlanta · 2017Article
- Herbaspirillum rubrisubalbicans, a mild pathogen impairs growth of rice by augmenting ethylene levels.Plant molecular biology · 2017Article
- A pivotal role of vacuolar H(+)-ATPase in regulation of lipid production in Phaeodactylum tricornutum.Scientific reports · 2016Article
- A subtracted cDNA library identifies genes up-regulated during PHOT1-mediated early step of de-etiolation in tomato (Solanum lycopersicum L.).BMC genomics · 2016Article
- MAPK-mediated enhanced expression of vacuolar H(+)-ATPase confers the improved adaption to NaCl stress in a halotolerate peppermint (Mentha piperita L.).Protoplasma · 2016Article
- MdMYB1 Regulates Anthocyanin and Malate Accumulation by Directly Facilitating Their Transport into Vacuoles in Apples.Plant physiology · 2016Article
- Overexpression of ThVHAc1 and its potential upstream regulator, ThWRKY7, improved plant tolerance of Cadmium stress.Scientific reports · 2016Article
- Conserved V-ATPase c subunit plays a role in plant growth by influencing V-ATPase-dependent endosomal trafficking.Plant biotechnology journal · 2016Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acidification of intracellular compartments by the vacuolar-type H(+)-ATPases (VHA) is known to energize ion and metabolite transport, though cellular processes influenced by this activity are poorly understood. At least 26 VHA genes encode 12 subunits of the V(1)V(o)-ATPase complex in Arabidopsis, and how the expression, assembly, and activity of the pump are integrated into signaling networks that govern growth and adaptation are largely unknown. The role of multiple VHA-c genes encoding the 16-kD subunit of the membrane V(o) sector was investigated. Expression of VHA-c1, monitored by promoter-driven beta-glucuronidase (GUS) activity was responsive to light or dark in an organ-specific manner. VHA-c1 expression in expanding cotyledons, hypocotyls of etiolated seedlings, and elongation zone of roots supported a role for V-ATPase in cell enlargement. Mutants reduced in VHA-c1 transcript using dsRNA-mediated interference showed reduction in root growth relative to wild-type seedlings. In contrast, VHA-c3 promoter::GUS expression was undetectable in most organs of seedlings, but strong in the root cap. Interestingly, dsRNA-mediated mutants of vha-c3 also showed reduced root length and decreased tolerance to moderate salt stress. The results suggest that V-ATPase functions in the root cap influenced root growth. Expression of VHA-c1 and VHA-c3 in tissues with active membrane flow, including root cap, vascular strands, and floral style would support a model for participation of the V(o) sector and V(1)V(o)-ATPase in membrane trafficking and fusion. Two VHA-c genes are thus differentially expressed to support growth in expanding cells and to supply increased demand for V-ATPase in cells with active exocytosis.
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