ArticleClinical and molecular allergy : CMA2004
Dermatology for the practicing allergist: Tinea pedis and its complications.
Article in Clinical and molecular allergy : CMA, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 67 citations in OpenAlex.
- Non-coding RNAs in dermatophytosis: Key regulators of host-fungal interactions and pathogenesis-A review.Virulence · 2026Review
- A theranostic wearable laser-induced graphene-hydrogel dressing for synergistic treatment and real-time monitoring of dermatophytosis.Bioactive materials · 2026Article
- Methodological considerations in keratinophilic fungal infections study.The Indian journal of medical research · 2026Article
- Association between atopic dermatitis and dermatophytosis: A TriNetX retrospective cohort study.Journal of the American Academy of Dermatology · 2026Article
- Article
- Zoonotic and Anthropophilic Trichophyton mentagrophytes Complex Infection in Human: An Update and Narrative Review.Mycoses · 2025Review
- Prevalence of tinea pedis among adults in primary health care settings in Qatar: A cross-sectional study.Qatar medical journal · 2025Article
- Comprehensive Review on Tinea Infection Therapies: Allopathic and Herbal Approaches for Dermatophytosis.Recent advances in anti-infective drug discovery · 2025Review
- Infection patterns of scabies and tinea between inland and resettled indigenous Negrito communities in Peninsular Malaysia.PLoS neglected tropical diseases · 2024Article
- Expert Panel Review of Skin and Hair Dermatophytoses in an Era of Antifungal Resistance.American journal of clinical dermatology · 2024Review
- Atypical and Unpredictable Superficial Mycosis Presentations: A Narrative Review.Journal of fungi (Basel, Switzerland) · 2024Review
- Gram-Negative Toe Web Infections.Dermatology practical & conceptual · 2024Review
- Dermatophyte Infections Worldwide: Increase in Incidence and Associated Antifungal Resistance.Life (Basel, Switzerland) · 2023Review
- Article
- Pathogenesis, Immunology and Management of Dermatophytosis.Journal of fungi (Basel, Switzerland) · 2021Review
- Fungal infections of the feet in patients with erysipelas of the lower limb: is it a significant clinical problem?Infection · 2021Article
- Exaggerated Immune Reaction to Trichophyton Fungus Results in an Inflammatory Tinea Pedis.Archives of internal medicine research · 2020Article
- Prevalence and associated factors of skin diseases in aged nursing home residents: a multicentre prevalence study.BMJ open · 2017Observational
- New Antifungal Agents and New Formulations Against Dermatophytes.Mycopathologia · 2017Review
- Study of the Etiological Causes of Toe Web Space Lesions in Cairo, Egypt.Dermatology research and practice · 2015Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tinea pedis is a chronic fungal infection of the feet, very often observed in patients who are immuno-suppressed or have diabetes mellitus. The practicing allergist may be called upon to treat this disease for various reasons. Sometimes tinea infection may be mistaken for atopic dermatitis or allergic eczema. In other patients, tinea pedis may complicate allergy and asthma and may contribute to refractory atopic disease. Patients with recurrent cellulitis may be referred to the allergist/immunologist for an immune evaluation and discovered to have tinea pedis as a predisposing factor. From a molecular standpoint, superficial fungal infections may induce a type2 T helper cell response (Th2) that can aggravate atopy. Th2 cytokines may induce eosinophil recruitment and immunoglobulin E (IgE) class switching by B cells, thereby leading to exacerbation of atopic conditions. Three groups of fungal pathogens, referred to as dermatophytes, have been shown to cause tinea pedis: Trychophyton sp, Epidermophyton sp, and Microsporum sp. The disease manifests as a pruritic, erythematous, scaly eruption on the foot and depending on its location, three variants have been described: interdigital type, moccasin type, and vesiculobullous type. Tinea pedis may be associated with recurrent cellulitis, as the fungal pathogens provide a portal for bacterial invasion of subcutaneous tissues. In some cases of refractory asthma, treatment of the associated tinea pedis infection may induce remission in airway disease. Very often, protracted topical and/or oral antifungal agents are required to treat this often frustrating and morbid disease. An evaluation for underlying immuno-suppression or diabetes may be indicated in patients with refractory disease.
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Registered trials
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