ArticleThorax2004
The need to redefine non-cystic fibrosis bronchiectasis in childhood.
Article in Thorax, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02555865 (Aetiology of Children With Bronchiectasis in China--A Multicenter Retrospective Study), which is not on this map. Cited by 55 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Aetiology of Children With Bronchiectasis in China--A Multicenter Retrospective Study
Who cites it
55 citing papers in PubMed, 5 syntheses or guidelines pooled it, 196 citations in OpenAlex.
- Management of Adult Bronchiectasis: Consensus-Based Guidelines of the German Respiratory Society.Respiration; international review of thoracic diseases · 2026Guideline
- Exercise training for bronchiectasis.The Cochrane database of systematic reviews · 2021Pooled it
- Head-to-head trials of antibiotics for bronchiectasis.The Cochrane database of systematic reviews · 2018Pooled it
- Distribution of Major Pathogens from Sputum and Bronchoalveolar Lavage Fluid in Patients with Noncystic Fibrosis Bronchiectasis: A Systematic Review.Chinese medical journal · 2015Pooled it
- The etiologies of non-CF bronchiectasis in childhood: a systematic review of 989 subjects.BMC pediatrics · 2014Pooled it
- Bronchiectasis in Inborn Errors of Immunity: Prevalence, Predictors, and Cardiopulmonary Complications in a Genetically Characterized Cohort.Journal of clinical immunology · 2026Observational
- Pediatric bronchiectasis-the importance of early diagnosis of children across the chronic wet cough spectrum.Journal of thoracic disease · 2025Review
- Lung function trajectories in children with early diagnosis of non-cystic fibrosis bronchiectasis: a retrospective observational study.Italian journal of pediatrics · 2024Observational
- Cough in Protracted Bacterial Bronchitis and Bronchiectasis.Journal of clinical medicine · 2024Article
- Time to re-set our thinking about airways disease: lessons from history, the resurgence of chronic bronchitis / PBB and modern concepts in microbiology.Frontiers in pediatrics · 2024Review
- ERS International Virtual Congress 2021: Highlights from the Turkish Thoracic Society Early Career Members.Turkish thoracic journal · 2022Article
- Monitoring disease progression in childhood bronchiectasis.Frontiers in pediatrics · 2022Review
- The radiological diagnosis of bronchiectasis: what's in a name?European respiratory review : an official journal of the European Respiratory Society · 2020Review
- Changing clinical characteristics of non-cystic fibrosis bronchiectasis in children.BMC pulmonary medicine · 2020Observational
- Bronchiectasis in Primary Antibody Deficiencies: A Multidisciplinary Approach.Frontiers in immunology · 2020Review
- Review
- Evaluation of Noncystic Fibrosis Bronchiectasis Using Clinical and Radiological Scorings in Children.Turkish thoracic journal · 2018Article
- Health care experiences of mothers of children with bronchiectasis in Counties Manukau, Auckland, New Zealand.BMC health services research · 2018Article
- Review
- Gender differences in bronchiectasis: a real issue?Breathe (Sheffield, England) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNon-cystic fibrosis (CF) bronchiectasis has previously been reported to be rare and progressive in children living in western societies.
methodA clinical and radiological review was undertaken of 93 children with non-CF bronchiectasis defined by high resolution computed tomographic (HRCT) scanning presenting to a tertiary paediatric respiratory centre since 1996.
resultsCases constituted 9.6% of all new referrals. Male to female ratio was 2:1. Median age at symptom onset was 1.1 years (range 0-16) and of HRCT diagnosis was 7.2 years (1.6-18.8). The most common referral diagnosis of asthma was refuted in 39 of 45 cases. Associations were previous pneumonic illness (30%), immunocompromise (21%), obliterative bronchiolitis (9%), congenital lung abnormality (5%), chronic aspiration (3%), eosinophilic oesophagitis (2%), familial syndrome (2%), primary ciliary dyskinesia (1%), and right middle lobe syndrome (1%). 8% had two associated diagnoses and 18% were idiopathic. There was agreement between the chest radiograph and HRCT scan for diagnosis and lobe affected in only five cases (5%). A repeat HRCT scan in 18 cases at a minimum interval of 18 months showed total resolution of the changes in six, improvement in one, progression in five, and was unchanged in six.
conclusionsRadiologically defined non-CF bronchiectasis in children is not uncommon. Diagnostic delay is a problem. The most common association is a previous pneumonia. Chest radiography is of little diagnostic value, but resolution is possible on HRCT scanning. Bronchiectasis is currently defined as a condition which is both permanent and progressive. This term is not necessarily appropriate for all paediatric patients for whom we suggest an alternative nomenclature.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.