Evidence map›Paper›PMID 15047557›Full record

ArticleAntimicrobial agents and chemotherapy2004

Identification of the Haemophilus influenzae tolC gene by susceptibility profiles of insertionally inactivated efflux pump mutants.

Catherine M Trepod, John E Mott

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  3. Amino acid substitutions in the region between RpoB clusters II and III on rifampin susceptibility in Haemophilus influenzae.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Catherine M TrepodAntibacterials, Pfizer, Groton, Connecticut 06340, USA. catherine.m.trepod@pfizer.com
John E Mott
Pfizer (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isogenic strains containing insertional disruptions of 10 Haemophilus influenzae Rd genes were investigated for their effects on the susceptibility of the organism to various classes of antimicrobial compounds. MIC results show that HI1462, which encodes an Escherichia coli TolC homolog, is the third component of the H. influenzae AcrAB pump.

Indexed as

ATP-Binding Cassette, Sub-Family C ProteinsBacterial Outer Membrane ProteinsCarrier ProteinsDNA, BacterialDNA Transposable ElementsEscherichia coliEscherichia coli ProteinsHaemophilus influenzaeLipoproteinsMembrane ProteinsMembrane Transport ProteinsMutagenesis, InsertionalMutationOligonucleotidesAcrA protein, E coliAcrB protein, E coliATP-Binding Cassette, Sub-Family C ProteinsBacterial Outer Membrane ProteinsCarrier ProteinsDNA, BacterialDNA Transposable ElementsEscherichia coli ProteinsLipoproteinsMembrane ProteinsMembrane Transport ProteinsOligonucleotidestolC protein, E coli

Identifiers

PMID15047557
PMCPMC375248
OpenAlexW2111396311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.