ArticleVirchows Archiv : an international journal of pathology2004
Mucosa-associated lymphoid tissue lymphoma in the conjunctiva of a child.
Article in Virchows Archiv : an international journal of pathology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 23 citations in OpenAlex.
- Conjunctival Lymphoma.Eye (London, England) · 2023Review
- Extranodal Ocular Adnexal Marginal Zone Lymphoma in a Ten-Year-Old ChildTurkish journal of ophthalmology · 2020Article
- Paediatric ocular adnexal lymphoma: a population-based analysis.BMJ open ophthalmology · 2020Article
- An Unusual Presentation of Pediatric Conjunctival Mucosa-Associated Lymphoid Tissue Lymphoma.Case reports in ophthalmological medicine · 2019Article
- Translocation (5; 11) in a conjunctival MALT lymphoma.International journal of clinical and experimental pathology · 2011Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT) occurring in the conjunctiva has yet not been described in pediatric patients. We present a case of a 10-year-old girl with a MALT lymphoma involving the conjunctiva. The tumor consisted of plasma cells and marginal zone cells with discrete epitheliotropism. Immunohistochemical studies revealed positivity for CD20 and cytoplasmic immunoglobulin lambda light chain restriction. Polymerase chain reaction-based molecular analysis of the infiltrate showed a monoclonal rearrangement for the hypervariable complimentary determining region III immunoglobulin region; whereas, a polyclonal pattern was seen for the T-cell receptor gamma chain. Extensive further examination, including molecular techniques, revealed that the lymphoma was restricted to the conjunctiva (stage IA) and was not associated with any specific infection. The patient was treated with surgery and additional local cryotherapy. After 15 months of follow-up, the patient remains in complete remission.
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