ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2004
Corticofugal gating of auditory information in the thalamus: an in vivo intracellular recording study.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 81 citations in OpenAlex.
- The lipidomic architecture of the mouse brain.Nature · 2026Article
- Organization of orbitofrontal-auditory pathways in the Mongolian gerbil.The Journal of comparative neurology · 2023Article
- Thalamocortical loops as temporal demodulators across senses.Communications biology · 2023Review
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- Article
- Mechanisms of GABAergic and cholinergic neurotransmission in auditory thalamus: Impact of aging.Hearing research · 2021Review
- Effects of Cortical Cooling on Sound Processing in Auditory Cortex and Thalamus of Awake Marmosets.Frontiers in neural circuits · 2021Article
- Corticothalamic Pathways in Auditory Processing: Recent Advances and Insights From Other Sensory Systems.Frontiers in neural circuits · 2021Review
- Lemniscal Corticothalamic Feedback in Auditory Scene Analysis.Frontiers in neuroscience · 2021Review
- When and How Does the Auditory Cortex Influence Subcortical Auditory Structures? New Insights About the Roles of Descending Cortical Projections.Frontiers in neuroscience · 2021Review
- Laser-Induced Apoptosis of Corticothalamic Neurons in Layer VI of Auditory Cortex Impact on Cortical Frequency Processing.Frontiers in neural circuits · 2021Article
- Post-stimulatory activity in primate auditory cortex evoked by sensory stimulation during passive listening.Scientific reports · 2020Article
- Top-Down Inference in the Auditory System: Potential Roles for Corticofugal Projections.Frontiers in neural circuits · 2020Review
- Article
- Ionic Mechanism Underlying Rebound Depolarization in Medial Prefrontal Cortex Pyramidal Neurons.Frontiers in cellular neuroscience · 2018Article
- Presynaptic Neuronal Nicotinic Receptors Differentially Shape Select Inputs to Auditory Thalamus and Are Negatively Impacted by Aging.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Robotic navigation to subcortical neural tissue for intracellular electrophysiology in vivo.Journal of neurophysiology · 2017Article
- A Role for Auditory Corticothalamic Feedback in the Perception of Complex Sounds.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Asymmetries of Dark and Bright Negative Afterimages Are Paralleled by Subcortical ON and OFF Poststimulus Responses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
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Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present study, we investigated the auditory responses of the medial geniculate (MGB) neurons, through in vivo intracellular recordings of anesthetized guinea pigs, while the auditory cortex was electrically activated. Of the 63 neurons that received corticofugal modulation of the membrane potential, 30 received potentiation and 33 received hyperpolarization. The corticofugal potentiation of the membrane potential (amplitude, mean +/- SD, 8.6 +/- 5.5 mV; duration, 125.5 +/- 75.4 msec) facilitated the auditory responses and spontaneous firing of the MGB neurons. The hyperpolarization of -11.3 +/- 4.9 mV in amplitude and 210.0 +/- 210.1 msec in duration suppressed the auditory responses and spontaneous firing of the MGB neurons. Four of the five neurons that were histologically confirmed to be located in the lemniscal MGB received corticofugal facilitatory modulation, and all of the four neurons that were confirmed to be located in the non-lemniscal MGB received corticofugal inhibitory modulation. The present intracellular recording provides novel results on how the corticofugal projection gates the sensory information in the thalamus: via the spatially selective depolarization of lemniscal MGB neurons and hyperpolarization of non-lemniscal MGB neurons. It is speculated that the systematic selectivity of facilitation and inhibition over the lemniscal and non-lemniscal MGB is related to the attention shift within the auditory modality and across the sensory modalities.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.