Evidence map›Paper›PMID 15040260›Full record

ReviewNature reviews. Microbiology2004

Pathogenic Escherichia coli.

James B Kaper, James P Nataro, Harry L Mobley

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2,335 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2,335citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2,335 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Extended spectrum beta lactamases and carbapenemase-producingOne health (Amsterdam, Netherlands) · 2026
    Review
  12. Article
  13. Article
  14. Whole-genome surveillance supports hazard profiling ofApplied and environmental microbiology · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

2,275 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James B KaperCenter for Vaccine Development, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. jkaper@umaryland.edu
James P Nataro
Harry L Mobley

Funding

Molecular Genetics of Enteropathogenic E. Coli AdhesionR37AI021657 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KAPER, JAMES B · 2004 to 2013
$4.8M
NIAID NIH HHS R37 AI021657
6 · The paper itself

Abstract

Few microorganisms are as versatile as Escherichia coli. An important member of the normal intestinal microflora of humans and other mammals, E. coli has also been widely exploited as a cloning host in recombinant DNA technology. But E. coli is more than just a laboratory workhorse or harmless intestinal inhabitant; it can also be a highly versatile, and frequently deadly, pathogen. Several different E. coli strains cause diverse intestinal and extraintestinal diseases by means of virulence factors that affect a wide range of cellular processes.

Indexed as

AnimalsBacterial AdhesionDiarrheaEscherichia coliGene Expression Regulation, BacterialHumansMeningitis, BacterialShiga ToxinsUrinary Tract InfectionsVirulence FactorsShiga ToxinsVirulence Factors

Identifiers

PMID15040260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.