Evidence map›Paper›PMID 15039380›Full record

ArticleInfection and immunity2004

Salmonella flagellin is not a dominant protective antigen in oral immunization with attenuated live vaccine strains.

Chie Kodama, Hidenori Matsui

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  4. Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
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  11. Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen.Proceedings of the National Academy of Sciences of the United States of America · 2004
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Chie KodamaKitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Hidenori Matsui
Kitasato Institute Hospital · JPKitasato University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We found that oral immunization with flagellum-defective mutant strains of Salmonella enterica serovar Typhimurium with the ClpXP-deficient background protected mice against oral challenge with the virulent strain. These data indicate that Salmonella flagellin is not a dominant protective antigen in oral immunization with attenuated live vaccine strains.

Indexed as

Adenosine TriphosphatasesAdministration, OralAnimalsAntibodies, BacterialAntigens, BacterialEndopeptidase ClpFemaleFlagellinGene DeletionImmunizationMiceMice, Inbred BALB CSalmonella Infections, AnimalSalmonella typhimuriumSalmonella VaccinesSerine EndopeptidasesAdenosine TriphosphatasesAntibodies, BacterialAntigens, BacterialEndopeptidase ClpFlagellinSalmonella VaccinesSerine EndopeptidasesVaccines, Attenuated

Identifiers

PMID15039380
PMCPMC375176
OpenAlexW2153613464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.