Evidence map›Paper›PMID 15038609›Full record

ReviewNeurochemical research2004

Redox control of signal transduction, gene expression and cellular senescence.

Franca Esposito, Rosario Ammendola, Raffaella Faraonio, Tommaso Russo, Filiberto Cimino

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurochemical research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 115 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. [Relationship among areca nut, intracellular reactive oxygen species, and autophagy].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2020
    Review
  7. The development of the concept of ferroptosis.Free radical biology & medicine · 2019
    Review
  8. Article
  9. Review
  10. Review
  11. Multifunctional Cinnamic Acid Derivatives.Molecules (Basel, Switzerland) · 2017
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. The emerging role of QSOX1 in cancer.Antioxidants & redox signaling · 2014
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Franca EspositoDipartimento di Biochimica e Biotecnologie Mediche, Università di Napoli Federico II, Naples, Italy.
Rosario Ammendola
Raffaella Faraonio
Tommaso Russo
Filiberto Cimino
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive oxygen species (ROS) act as subcellular messengers in such complex cellular processes as mitogenic signal transduction, gene expression, regulation of cell proliferation, replicative senescence, and apoptosis. They serve to maintain cellular homeostasis and their production is under strict control. However, the mechanisms whereby ROS act are still obscure. Here we review recent advances in our understanding of signaling mechanisms and recent data about the involvement of ROS in: (i) the regulation of the mitogenic transduction elements, particularly protein kinases and phosphatases; (ii) the regulation of gene expression; and (iii) the induction of replicative senescence and the role, if any, in aging and age-related disorders.

Indexed as

AnimalsCellular SenescenceGene Expression RegulationHumansMitogen-Activated Protein KinasesOxidation-ReductionReactive Oxygen SpeciesSecond Messenger SystemsSignal TransductionMitogen-Activated Protein KinasesReactive Oxygen Species

Identifiers

PMID15038609
OpenAlexW2089537636

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.