Trial reportArchives of disease in childhood2004
Bacteraemia and antibiotic use in respiratory syncytial virus infections.
Trial report in Archives of disease in childhood, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Antibiotics for preventing suppurative complications from undifferentiated acute respiratory infections in children under five years of age.The Cochrane database of systematic reviews · 2016Pooled it
- Antibiotics for bronchiolitis in children under two years of age.The Cochrane database of systematic reviews · 2014Pooled it
- Trial
- Burden of laboratory-confirmed RSV hospitalization in children <5 years-of-age; 2019-2022.BMC pediatrics · 2026Article
- Prevalence and risk factors of concurrent bacteremia in children under 5 years of age hospitalized with viral lower respiratory tract infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- Article
- Epidemiology and Outcomes of Bacterial Coinfection in Hospitalized Children With Respiratory Viral Infections: A Single Center Retrospective Chart Review.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2022Article
- Antibiotic use for respiratory syncytial virus in the Middle East: A surveillance study in hospitalized Jordanian children.PloS one · 2021Article
- Co-seasonality and co-detection of respiratory viruses and bacteraemia in children: a retrospective analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020Article
- Bacterial co-infection of the respiratory tract in ventilated children with bronchiolitis; a retrospective cohort study.BMC infectious diseases · 2019Article
- Healthcare resource use and economic burden attributable to respiratory syncytial virus in the United States: a claims database analysis.BMC health services research · 2018Article
- Incidence, Morbidity, and Costs of Human Metapneumovirus Infection in Hospitalized Children.Journal of the Pediatric Infectious Diseases Society · 2016Article
- Observational
- Bronchiolitis outbreak caused by respiratory syncytial virus in southwest Bangladesh, 2010.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2012Article
- Acute lower respiratory tract infection due to respiratory syncytial virus in a group of Egyptian children under 5 years of age.Italian journal of pediatrics · 2011Article
- Treatment of acute viral bronchiolitis.The open microbiology journal · 2011Article
- Influenza and parainfluenza associated pediatric ICU morbidity.Indian journal of pediatrics · 2010Article
- Severe childhood respiratory viral infections.Advances in pediatrics · 2009Review
- Premorbid factors and outcome associated with respiratory virus infections in a pediatric intensive care unit.Pediatric pulmonology · 2008Article
- Effect of point of care information on inpatient management of bronchiolitis.BMC pediatrics · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo examine the frequency of and risk factors for bacteraemia in children hospitalised with respiratory syncytial virus (RSV) infection; and to determine current use of antibiotics in hospitalised children with RSV infection.
methodsRetrospective study of all children, aged 0-14 years, admitted to a tertiary children's hospital with proven RSV infection over a four year period. Children with concurrent bacteraemia and RSV infection were identified, and risk factors examined for bacteraemia. The case notes of a randomly selected comparison sample of 100 of these RSV infected children were examined to assess antibiotic use and population incidence of risk factors for severe RSV infection.
resultsA total of 1795 children had proven RSV infection, and blood cultures were sent on 861 (48%). Eleven (0.6%) of the 1795 RSV positive children had bacteraemia. RSV positive children had a significantly higher incidence of bacteraemia if they had nosocomial RSV infection (6.5%), cyanotic congenital heart disease (6.6%), or were admitted to the paediatric intensive care unit (2.9%). Forty five (45%) of the random comparison sample of RSV infected children received antibiotics.
conclusionsBacteraemia is rare in RSV infection. Children with RSV infection are more likely to be bacteraemic, however, if they have nosocomial RSV infection, cyanotic congenital heart disease, or require intensive care unit admission.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.