ArticleThe Plant cell2004
Arabidopsis peptide methionine sulfoxide reductase2 prevents cellular oxidative damage in long nights.
Article in The Plant cell, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 123 citations in OpenAlex.
- Protein turnover in plants-cost of synthesis, repair, and crop engineering opportunities.Plant physiology · 2026Review
- Identification of the methionine sulfoxide reductase (MSR) gene family in four Triticum species and functional analysis of TaMSRB5 involved in copper stress tolerance in Arabidopsis thaliana.Plant molecular biology · 2026Article
- Modulation of the Arabidopsis Starch Metabolic Network by the Cytosolic Acetyl-CoA Pathway in the Context of the Diurnal Illumination Cycle.International journal of molecular sciences · 2024Article
- Phylogenetic conservation of the interdependent homeostatic relationship of sleep regulation and redox metabolism.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024Review
- Genome-Wide Identification and Characterization of the Msr Gene Family in Alfalfa under Abiotic Stress.International journal of molecular sciences · 2023Article
- Article
- Protein Glycation in Plants-An Under-Researched Field with Much Still to Discover.International journal of molecular sciences · 2020Review
- Peptide-Bound Methionine Sulfoxide (MetO) Levels and MsrB2 Abundance Are Differentially Regulated during the Desiccation Phase in ContrastedAntioxidants (Basel, Switzerland) · 2020Article
- Effects of Stripe Rust Infection on the Levels of Redox Balance and Photosynthetic Capacities in Wheat.International journal of molecular sciences · 2019Article
- Wheat methionine sulfoxide reductase A4.1 interacts with heme oxygenase 1 to enhance seedling tolerance to salinity or drought stress.Plant molecular biology · 2019Article
- Regulation of Gene Expression of Methionine Sulfoxide Reductases and Their New Putative Roles in Plants.International journal of molecular sciences · 2019Article
- Transcriptome-wide effects of expansin gene manipulation in etiolated Arabidopsis seedling.Journal of plant research · 2019Article
- Profiling of advanced glycation end products uncovers abiotic stress-specific target proteins in Arabidopsis.Journal of experimental botany · 2019Article
- The Oxidized Protein Repair Enzymes Methionine Sulfoxide Reductases and Their Roles in Protecting against Oxidative Stress, in Ageing and in Regulating Protein Function.Antioxidants (Basel, Switzerland) · 2018Review
- Comparison on Photosynthesis and Antioxidant Defense Systems in Wheat with Different Ploidy Levels and Octoploid Triticale.International journal of molecular sciences · 2018Article
- Physiological Roles of Plant Methionine Sulfoxide Reductases in Redox Homeostasis and Signaling.Antioxidants (Basel, Switzerland) · 2018Review
- Dark period transcriptomic and metabolic profiling of two diversePlant direct · 2018Article
- The Role of Light-Dark Regulation of the Chloroplast ATP Synthase.Frontiers in plant science · 2017Article
- Arabidopsis thaliana methionine sulfoxide reductase B8 influences stress-induced cell death and effector-triggered immunity.Plant molecular biology · 2017Article
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Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peptide methionine sulfoxide reductase (PMSR) is a ubiquitous enzyme that repairs oxidatively damaged proteins. In Arabidopsis (Arabidopsis thaliana), a null mutation in PMSR2 (pmsr2-1), encoding a cytosolic isoform of the enzyme, exhibited reduced growth in short-day conditions. In wild-type plants, a diurnally regulated peak of total PMSR activity occurred at the end of the 16-h dark period that was absent in pmsr2-1 plants. This PMSR activity peak in the wild-type plant coincided with increased oxidative stress late in the dark period in the mutant. In pmsr2-1, the inability to repair proteins resulted in higher levels of their turnover, which in turn placed an increased burden on cellular metabolism. This caused increased respiration rates, leading to the observed higher levels of oxidative stress. In wild-type plants, the repair of damaged proteins by PMSR2 at the end of the night in a short-day diurnal cycle alleviates this potential burden on metabolism. Although PMSR2 is not absolutely required for viability of plants, the observation of increased damage to proteins in these long nights suggests the timing of expression of PMSR2 is an important adaptation for conservation of their resources.
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