ReviewTraffic (Copenhagen, Denmark)2004
Lipid rafts and the regulation of exocytosis.
Review in Traffic (Copenhagen, Denmark), 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
99 citing papers in PubMed, 296 citations in OpenAlex.
- Glycosylated NS3/NS3A protein of bluetongue virus facilitates efficient viral egress via lipid raft anchoring.Journal of virology · 2026Article
- Neutrophil-derived vesicles control complement activation to facilitate inflammation resolution.Cell · 2025Article
- Lipids and Secretory Vesicle Exocytosis.Advances in neurobiology · 2023Article
- Sterols and Sphingolipids as New Players in Cell Wall Building and Apical Growth ofPlants (Basel, Switzerland) · 2022Article
- A new strategy to count and sort neutrophil-derived extracellular vesicles: Validation in infectious disorders.Journal of extracellular vesicles · 2022Article
- Anionic Species Regulate Chemical Storage in Nanometer Vesicles and Amperometrically Detected Exocytotic Dynamics.Journal of the American Chemical Society · 2022Article
- Role of the IgG4-related cholangitis autoantigen annexin A11 in cholangiocyte protection.Journal of hepatology · 2022Article
- Lysolipids regulate raft size distribution.Frontiers in molecular biosciences · 2022Article
- Studying IndependentThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Caveolin-1 deficiency impairs synaptic transmission in hippocampal neurons.Molecular brain · 2021Article
- Calcium-Prolactin Secretion Coupling in Rat Pituitary Lactotrophs Is Controlled by PI4-Kinase Alpha.Frontiers in endocrinology · 2021Article
- Counteranions in the Stimulation Solution Alter the Dynamics of Exocytosis Consistent with the Hofmeister Series.Journal of the American Chemical Society · 2020Article
- Proteomic Analysis of Lipid Rafts from RBL-2H3 Mast Cells.International journal of molecular sciences · 2019Article
- Enhanced Raman Investigation of Cell Membrane and Intracellular Compounds by 3D Plasmonic Nanoelectrode Arrays.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018Article
- The challenges of oral drug delivery via nanocarriers.Drug delivery · 2018Review
- Emerging evidence for the modulation of exocytosis by signalling lipids.FEBS letters · 2018Review
- Fluid Phase Coexistence in Biological Membrane: Insights from Local Nonaffine Deformation of Lipids.Biophysical journal · 2018Article
- P2X1 Receptors Amplify FcγRIIa-Induced Ca2+ Increases and Functional Responses in Human Platelets.Thrombosis and haemostasis · 2018Article
- The increased release of amino acid neurotransmitters of the primary somatosensory cortical area in rats contributes to remifentanil-induced hyperalgesia and its inhibition by lidocaine.Journal of pain research · 2018Article
- How do megakaryocytic microparticles target and deliver cargo to alter the fate of hematopoietic stem cells?Journal of controlled release : official journal of the Controlled Release Society · 2017Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Exocytosis is the process whereby intracellular fluid-filled vesicles fuse with the plasma membrane, incorporating vesicle proteins and lipids into the plasma membrane and releasing vesicle contents into the extracellular milieu. Exocytosis can occur constitutively or can be tightly regulated, for example, neurotransmitter release from nerve endings. The last two decades have witnessed the identification of a vast array of proteins and protein complexes essential for exocytosis. SNARE proteins fill the spotlight as probable mediators of membrane fusion, whereas proteins such as munc18/nsec1, NSF and SNAPs function as essential SNARE regulators. A central question that remains unanswered is how exocytic proteins and protein complexes are spatially regulated. Recent studies suggest that lipid rafts, cholesterol and sphingolipid-rich microdomains, enriched in the plasma membrane, play an essential role in regulated exocytosis pathways. The association of SNAREs with lipid rafts acts to concentrate these proteins at defined sites of the plasma membrane. Furthermore, cholesterol depletion inhibits regulated exocytosis, suggesting that lipid raft domains play a key role in the regulation of exocytosis. This review examines the role of lipid rafts in regulated exocytosis, from a passive role as spatial coordinator of exocytic proteins to a direct role in the membrane fusion reaction.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.