Evidence map›Paper›PMID 15028117›Full record

ArticleBMC bioinformatics2004

VisANT: an online visualization and analysis tool for biological interaction data.

Zhenjun Hu, Joseph Mellor, Jie Wu, Charles DeLisi

Abstract readComparative Study
In one paragraph

Article in BMC bioinformatics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed.

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  15. Immuno-Modulatory Effects of Intervertebral Disc Cells.Frontiers in cell and developmental biology · 2022
    Review
  16. Frontiers in bioinformatics · 2022
    Article
  17. Article
  18. Review
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  20. Article

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhenjun HuBioinformatics Program, Boston University, Boston, MA 02215, USA. zjhu@bu.edu
Joseph Mellor
Jie Wu
Charles DeLisi

Funding

PERTURBATION ANALYSIS OF PI3 KINASE /ERK SIGNALINGP20GM066401 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI DELISI, CHARLES · 2002 to 2004
$1.2M
NIGMS NIH HHS 1P20GM066401-01NIGMS NIH HHS P20 GM066401
6 · The paper itself

Abstract

backgroundNew techniques for determining relationships between biomolecules of all types--genes, proteins, noncoding DNA, metabolites and small molecules--are now making a substantial contribution to the widely discussed explosion of facts about the cell. The data generated by these techniques promote a picture of the cell as an interconnected information network, with molecular components linked with one another in topologies that can encode and represent many features of cellular function. This networked view of biology brings the potential for systematic understanding of living molecular systems.

resultsWe present VisANT, an application for integrating biomolecular interaction data into a cohesive, graphical interface. This software features a multi-tiered architecture for data flexibility, separating back-end modules for data retrieval from a front-end visualization and analysis package. VisANT is a freely available, open-source tool for researchers, and offers an online interface for a large range of published data sets on biomolecular interactions, including those entered by users. This system is integrated with standard databases for organized annotation, including GenBank, KEGG and SwissProt. VisANT is a Java-based, platform-independent tool suitable for a wide range of biological applications, including studies of pathways, gene regulation and systems biology.

conclusionVisANT has been developed to provide interactive visual mining of biological interaction data sets. The new software provides a general tool for mining and visualizing such data in the context of sequence, pathway, structure, and associated annotations. Interaction and predicted association data can be combined, overlaid, manipulated and analyzed using a variety of built-in functions. VisANT is available at http://visant.bu.edu.

Indexed as

SoftwareAnimalsComputational BiologyComputer GraphicsDatabase Management SystemsDatabases, GeneticGene Expression ProfilingGene Expression RegulationGenes, FungalGenes, HelminthHelminth ProteinsHumansMiceProtein Interaction MappingSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsHelminth ProteinsSaccharomyces cerevisiae ProteinsTranscription Factors

Identifiers

PMID15028117
PMCPMC368431

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.