Evidence map›Paper›PMID 15025448›Full record

ArticleJournal of the American Chemical Society2004

Direct detection of homocysteine.

Weihua Wang, Jorge O Escobedo, Candace M Lawrence, Robert M Strongin

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Thiol reactive probes and chemosensors.Sensors (Basel, Switzerland) · 2012
    Review
  10. Homocystamides promote free-radical and oxidative damage to proteins.Proceedings of the National Academy of Sciences of the United States of America · 2010
    Article
  11. Article
  12. Article
  13. Gold nanoparticle sensor for homocysteine thiolactone-induced protein modification.Langmuir : the ACS journal of surfaces and colloids · 2008
    Article
  14. Article
  15. Article
  16. Detection of homocysteine and cysteine.Journal of the American Chemical Society · 2005
    Article
  17. A convenient preparation of xanthene dyes.The Journal of organic chemistry · 2005
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Weihua WangDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, USA.
Jorge O Escobedo
Candace M Lawrence
Robert M Strongin

Funding

Synthesis and Study of Novel Sensing AgentsR01EB002044 · NIBIB · PORTLAND STATE UNIVERSITY · PI STRONGIN, ROBERT M · 2003 to 2010
$1.6M
A Simple and Robust Indicator for GlutathioneR15EB016870 · NIBIB · PORTLAND STATE UNIVERSITY · PI STRONGIN, ROBERT M · 2014 to 2014
$435k
NIBIB NIH HHS R01 EB002044NIBIB NIH HHS R15 EB016870
6 · The paper itself

Abstract

Homocysteine (Hcy) is a biomarker for significant disorders including Alzheimer's and cardiovascular disease. The monitoring of Hcy levels in plasma is of current concern. We describe highly selective colorimetric methods for the direct detection of Hcy. Inexpensive, commercially available materials are employed. The results show potential application for the detection of Hcy in human blood plasma.

Indexed as

ColorimetryHomocysteineHumansHydrogen-Ion ConcentrationParaquatSpectrophotometry, UltravioletHomocysteineParaquat

Identifiers

PMID15025448
PMCPMC3376413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.