Evidence map›Paper›PMID 15024601›Full record

ReviewWorld journal of urology2004

The role of positron emission tomography in germ cell cancer.

Maria De Santis, Jörg Pont

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of urology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. FDG PET Hybrid Imaging.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  4. Nuclear medicine imaging in non-seminomatous germ cell tumors: lessons learned from the past failures.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  5. Review
  6. Performance characteristics ofCanadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022
    Article
  7. Article
  8. 18F-FDG PET/CT impact on testicular tumours clinical management.European journal of nuclear medicine and molecular imaging · 2014
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Atypical basal ganglia germinoma presenting as cerebral hemiatrophy: diagnosis and follow-up with 11C-methionine positron emission tomography.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2009
    Article
  16. Review
  17. Management of urological malignancies: Has positron emission tomography/computed tomography made a difference?Indian journal of urology : IJU : journal of the Urological Society of India
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Maria De SantisDepartment of Medical Oncology, Kaiser Franz Josef Spital der Stadt Wien, Kundratstrasse 3, 1100 Wien, Austria.
Jörg Pont
Kaiser-Franz-Josef-Spital · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Positron emission tomography (PET) is a non-invasive tool for imaging regional metabolic processes, which adds another dimension to current anatomy-derived imaging techniques, i.e. metabolic imaging. To date, 2-(18)fluoro-2-deoxy-D-glucose (FDG) has been the only tracer used for imaging germ cell tumors (GCT), which can be distinguished from normal tissue by their different glucose utilization. However, FDG PET has several limitations: (1) inflammatory and granulomatous tissues also show extensive FDG uptake, (2) lesions <1 cm in size can often not be detected, and (3) mature teratoma is indistinguishable from normal and necrotic tissue. Studies assessing the clinical role of FDG PET in GCT suggest that the technique has a place as a standard tool in evaluating post chemotherapy seminoma residuals. Whether it also improves the assessment of the risks carried by clinical stage I non-seminoma patients and the early prediction of response to salvage chemotherapy is still under investigation, or at least needs to be confirmed by further trials. In relapsing patients with a mismatch between tumor markers and imaging data, FDG PET appears to be useful whenever salvage surgery is considered, although systematic trials are not yet available.

Indexed as

Tomography, Emission-ComputedAntineoplastic AgentsCisplatinFluorodeoxyglucose F18GerminomaHumansNeoplasm Recurrence, LocalNeoplasm, ResidualNeoplasm StagingRadiopharmaceuticalsAntineoplastic AgentsCisplatinFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID15024601
OpenAlexW2060412601

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.