ArticleMolecular and cellular biology2004
Histone fold protein Dls1p is required for Isw2-dependent chromatin remodeling in vivo.
Article in Molecular and cellular biology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- The WAC-downWAC domain in the yeast ISW2 nucleosome remodeling complex forms a structural module essential for ISW2 function but not cell viability.Epigenetics & chromatin · 2025Article
- Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes.Nature communications · 2021Article
- Yeast chromatin remodeling complexes and their roles in transcription.Current genetics · 2020Review
- Chromatin remodeling factors Isw2 and Ino80 regulate checkpoint activity and chromatin structure in S phase.Genetics · 2015Article
- Regulation of ISWI chromatin remodelling activity.Chromosoma · 2014Review
- ISWI chromatin remodeling: one primary actor or a coordinated effort?Current opinion in structural biology · 2014Review
- Article
- ATP-dependent chromatin remodeling factors tune S phase checkpoint activity.Molecular and cellular biology · 2011Article
- Patterns and mechanisms of ancestral histone protein inheritance in budding yeast.PLoS biology · 2011Article
- Alterations in DNA replication and histone levels promote histone gene amplification in Saccharomyces cerevisiae.Genetics · 2010Article
- DNA polymerase epsilon, acetylases and remodellers cooperate to form a specialized chromatin structure at a tRNA insulator.The EMBO journal · 2009Article
- Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.Molecular and cellular biology · 2009Article
- Multiple histone modifications in euchromatin promote heterochromatin formation by redundant mechanisms in Saccharomyces cerevisiae.BMC molecular biology · 2009Article
- Conformational changes associated with template commitment in ATP-dependent chromatin remodeling by ISW2.Molecular cell · 2009Article
- Kinetic mechanism for single-stranded DNA binding and translocation by Saccharomyces cerevisiae Isw2.Biochemistry · 2009Article
- A proteomics analysis of yeast Mot1p protein-protein associations: insights into mechanism.Molecular & cellular proteomics : MCP · 2008Article
- Site-specific cross-linking of TBP in vivo and in vitro reveals a direct functional interaction with the SAGA subunit Spt3.Genes & development · 2008Article
- DNA polymerase epsilon: a polymerase of unusual size (and complexity).Progress in nucleic acid research and molecular biology · 2008Review
- Special type of pheromone-induced invasive growth in Saccharomyces cerevisiae.Current genetics · 2007Article
- Dependency of ISW1a chromatin remodeling on extranucleosomal DNA.Molecular and cellular biology · 2007Article
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3 authors.
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Abstract
We report the identification of two new subunits of the Isw2 chromatin-remodeling complex in Saccharomyces cerevisiae. Both proteins, Dpb4p and Yjl065cp (named Dls1p), contain histone fold motifs and are homologous to the two smallest subunits of ISWI-containing CHRAC complexes in higher eukaryotes. Dpb4p is also a subunit of the DNA polymerase epsilon (polepsilon) complex, and Dls1p is homologous to another polepsilon subunit, Dpb3p. Therefore, these small histone fold proteins may fulfill functions that are required for both polepsilon and Isw2 complexes. We characterized the role of Dls1p in known roles of the Isw2 complex in vivo. Transcriptional analyses reveal that the Isw2 complex requires Dls1p to various degrees at a wide variety of loci in vivo. Consistent with this, Dls1p is required for Isw2-dependent chromatin remodeling in vivo, although the requirement for this protein varies among Isw2 targets. Dls1p is likely required for functions of the Isw2 complex at steps subsequent to its interaction with chromatin, since a dls1 mutation does not affect cross-linking of Isw2 with chromatin.
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