ArticleEuropean journal of clinical pharmacology2004
Drug utilisation in outpatient children. A comparison among Tenerife, Valencia, and Barcelona (Spain), Toulouse (France), Sofia (Bulgaria), Bratislava (Slovakia) and Smolensk (Russia).
Article in European journal of clinical pharmacology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pediatric Outpatient Prescriptions in Countries With Advanced Economies in the 21st Century: A Systematic Review.JAMA network open · 2022Pooled it
- Patterns of complementary and alternative medicine (CAM) use in children: a systematic review.European journal of pediatrics · 2014Pooled it
- Enabling factors for antibiotic prescribing for upper respiratory tract infections: perspectives of Lithuanian and Russian general practitioners.Upsala journal of medical sciences · 2013Article
- Methods in pharmacoepidemiology: a review of statistical analyses and data reporting in pediatric drug utilization studies.European journal of clinical pharmacology · 2013Review
- Drug utilization and off-label drug use among Spanish emergency room paediatric patients.European journal of clinical pharmacology · 2010Article
- Medication consumption in the Spanish paediatric population: related factors and time trend, 1993-2003.British journal of clinical pharmacology · 2009Article
- Drug prescriptions to outpatient children: a review of the literature.European journal of clinical pharmacology · 2009Review
- Drug utilisation profile in the Italian paediatric population.European journal of pediatrics · 2009Article
- Stimulation programs for pediatric drug research--do children really benefit?European journal of pediatrics · 2007Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionScarce information about comparative diagnostic and therapeutic patterns in paediatric outpatients of different countries is found in the literature.
objectiveTo describe the similarities and differences observed in diagnosis and therapeutic patterns of paediatric patients of seven locations in different countries.
designCross-sectional, prospective, international comparative, descriptive study. PATIENTS AND
methodsA randomly selected sample of 12,264 paediatric outpatients seen in consultation rooms of urban and rural areas and attended by paediatricians or general practitioners of the participating locations. Data on patient demographic information, diagnosis and pharmacological treatment were collected using pre-designed forms. Diagnoses were coded using the ICD-9 and drugs according to the ATC classification.
resultsAmong the ten most common diagnoses, upper respiratory tract infections are in the first position in all locations; asthma prevalence is highest in Tenerife (8.4%). Tonsillitis, otitis, bronchitis and dermatological affections are the most common diagnoses in all locations. Pneumonia is only reported in Sofia (3.8%) and Smolensk (2.3%). The average number of drugs prescribed per child varied from 1.3 in Barcelona to 2.9 in Smolensk. There are no great differences in the profile of pharmacological groups prescribed, but a considerable range of variations in antibiotic therapy is observed: prescription of cephalosporins is low in Smolensk (0.7%) and higher in the other locations, from 16.5% (Bratislava) to 28% (Tenerife). Macrolides prescriptions range from 12.6% (Toulouse) to 24.7% (Smolensk), except in Sofia where they drop to 5.6%. Trimethoprim and its combinations are used in Smolensk (23.3%), Sofia (11.8%) and Bratislava (8.7%). Check-up consultations are not recorded in Smolensk and Bratislava, whereas in Toulouse these visits account for 16.2% of all consultations and in the other locations the percentage varies from 6.1% (Tenerife) to 1.9% (Sofia). Homeopathic treatments are registered only in Toulouse.
conclusionExcept in asthma prevalence, there are no great differences in diagnostic maps among locations. Significant variations in the number of drugs prescribed per child and antibiotic therapies are observed. Areas for improvement have been identified.
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