ArticleThe Plant cell2004
Purification and characterization of serine proteases that exhibit caspase-like activity and are associated with programmed cell death in Avena sativa.
Article in The Plant cell, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed, 1 synthesis or guideline pooled it, 276 citations in OpenAlex.
- The front line of defence: a meta-analysis of apoplastic proteases in plant immunity.Journal of experimental botany · 2021Pooled it
- Genome-wide identification of the MCA gene family and its role in resistance to powdery mildew in wheat.BMC plant biology · 2026Article
- Plant caspase-like proteins: from function identification to application in winter rapeseed genetic breeding.Frontiers in plant science · 2026Review
- De novo transcriptome assembly and gene expression analysis of Cnidium officinale under high-temperature conditions.BMC genomics · 2025Article
- Multi-scale phenotyping of senescence-related changes in roots of rapeseed in response to nitrate limitation.Journal of experimental botany · 2025Article
- Perception and processing of stress signals by plant mitochondria.The Plant journal : for cell and molecular biology · 2024Review
- Cathepsin B degrades RbcL during freezing-induced programmed cell death in Arabidopsis.Plant cell reports · 2024Article
- Article
- A putative SUBTILISIN-LIKE SERINE PROTEASE 1 (SUBSrP1) regulates anther cuticle biosynthesis and panicle development in rice.Journal of advanced research · 2022Article
- Ambivalent response in pathogen defense: A double-edged sword?Plant communications · 2022Review
- Plant cell responses to allelopathy: from oxidative stress to programmed cell death.Protoplasma · 2022Review
- Comparative transcriptome analysis of resistant and susceptible wheat in response to Rhizoctonia cerealis.BMC plant biology · 2022Article
- Microbial interaction mediated programmed cell death in plants.3 Biotech · 2022Review
- Differing Responses toFrontiers in plant science · 2022Article
- Determination of Caspase-Like Activities in Roots by the Use of Fluorogenic Substrates.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Apoptosis is not conserved in plants as revealed by critical examination of a model for plant apoptosis-like cell death.BMC biology · 2021Article
- Review
- Cell Death in Cyanobacteria: Current Understanding and Recommendations for a Consensus on Its Nomenclature.Frontiers in microbiology · 2021Review
- Copper treatment of peach leaves causes lesion formation similar to the biotic stress response.Plant biotechnology (Tokyo, Japan) · 2019Article
- Quantitative Proteomic Analysis Reveals Novel Insights into Intracellular Silicate Stress-Responsive Mechanisms in the DiatomInternational journal of molecular sciences · 2019Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Victoria blight of Avena sativa (oat) is caused by the fungus Cochliobolus victoriae, which is pathogenic because of the production of the toxin victorin. The victorin-induced response in sensitive A. sativa has been characterized as a form of programmed cell death (PCD) and displays morphological and biochemical features similar to apoptosis, including chromatin condensation, DNA laddering, cell shrinkage, altered mitochondrial function, and ordered, substrate-specific proteolytic events. Victorin-induced proteolysis of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) is shown to be prevented by caspase-specific and general protease inhibitors. Evidence is presented for a signaling cascade leading to Rubisco proteolysis that involves multiple proteases. Furthermore, two proteases that are apparently involved in the Rubisco proteolytic cascade were purified and characterized. These proteases exhibit caspase specificity and display amino acid sequences homologous to plant subtilisin-like Ser proteases. The proteases are constitutively present in an active form and are relocalized to the extracellular fluid after induction of PCD by either victorin or heat shock. The role of the enzymes as processive proteases involved in a signal cascade during the PCD response is discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.