ArticleThe Journal of physiology2004
Lumbar sympathetic nerve activity and hindquarter blood flow during REM sleep in rats.
Article in The Journal of physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 54 citations in OpenAlex.
- Control of Blood Pressure Variability Across Behavioral States by Brainstem Adrenergic Neurons.Circulation research · 2026Article
- Sympathoexcitatory responses to renal chemosensitive stimuli are exaggerated at nighttime in rats.American journal of physiology. Heart and circulatory physiology · 2022Article
- Antihypertensive Mechanism of Orally Administered Acetylcholine in Spontaneously Hypertensive Rats.Nutrients · 2022Article
- Regional Differences in Sympathetic Nerve Activity Are Generated by Multiple Arterial Baroreflex Loops Arranged in Parallel.Frontiers in physiology · 2022Review
- Impact of anesthesia, sex, and circadian cycle on renal afferent nerve sensitivity.American journal of physiology. Heart and circulatory physiology · 2021Article
- Recording sympathetic nerve activity in conscious humans and other mammals: guidelines and the road to standardization.American journal of physiology. Heart and circulatory physiology · 2017Review
- Article
- Recording sympathetic nerve activity chronically in rats: surgery techniques, assessment of nerve activity, and quantification.American journal of physiology. Heart and circulatory physiology · 2013Review
- Translational physiology and SND recordings in humans and rats: a glimpse of the recent past with an eye on the future.Autonomic neuroscience : basic & clinical · 2013Review
- Optogenetic stimulation of c1 and retrotrapezoid nucleus neurons causes sleep state-dependent cardiorespiratory stimulation and arousal in rats.Hypertension (Dallas, Tex. : 1979) · 2013Article
- Article
- Chronic angiotensin II infusion causes differential responses in regional sympathetic nerve activity in rats.Hypertension (Dallas, Tex. : 1979) · 2010Article
- Effects of sinoaortic denervation on hemodynamic parameters during natural sleep in rats.Sleep · 2008Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study aimed to investigate the response of lumbar sympathetic nerve activity (LSNA) to the onset of rapid eye movement (REM) sleep and its contribution to the regulation of muscle blood flow during REM sleep in rats. Electrodes for the measurements of LSNA, electroencephalogram, electromyogram and electrocardiogram and a Doppler flow cuff for the measurements of blood flow in the common iliac and mesenteric arteries, also catheters for the measurements of systemic arterial and central venous pressures were implanted chronically. REM sleep resulted in a step increase in LSNA, by 22 +/- 9% (mean +/-S.E.M., P < 0.05), a reduction of iliac vascular conductance, by -16 +/- 3% (P < 0.05) and a gradual increase in systemic arterial pressure, reaching a maximum value of 8.1 +/- 2.0 mmHg (P < 0.05) at 89 s after onset of REM sleep, while mesenteric vascular conductance increased simultaneously by 5 +/- 2% (P < 0.05). There was a significant (Pearson's correlation coefficient = 0.94, P < 0.05) inverse linear relationship between LSNA and the iliac blood flow. Unilateral lumbar sympathectomy blunted the reduction of iliac blood flow induced by the onset of REM sleep. The present observations suggest that the onset of REM sleep appears to be associated with a vasodilation in viscera and a vasoconstriction in skeletal muscle, such that systemic arterial pressure increases during REM sleep in rats.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.