ArticleGenetics2004
Hybrid breakdown caused by substitution of the X chromosome between two mouse subspecies.
Article in Genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
63 citing papers in PubMed.
- Hybrid breakdown in male reproduction between recently diverged Drosophila melanogaster populations has a complex and variable genetic architecture.Evolution; international journal of organic evolution · 2023Article
- Investigating the Impact of a Curse: Diseases, Population Isolation, Evolution and the Mother's Curse.Genes · 2022Review
- Genic and chromosomal components of Prdm9-driven hybrid male sterility in mice (Mus musculus).Genetics · 2022Article
- Stage-specific disruption of X chromosome expression during spermatogenesis in sterile house mouse hybrids.G3 (Bethesda, Md.) · 2022Article
- Disrupted Gene Networks in Subfertile Hybrid House Mice.Molecular biology and evolution · 2020Article
- A high-throughput method for unbiased quantitation and categorization of nuclear morphology†.Biology of reproduction · 2019Article
- Genetic basis to hybrid inviability is more complex than hybrid male sterility in Caenorhabditis nematodes.Heredity · 2018Article
- Article
- Genome-wide association for testis weight in the diversity outbred mouse population.Mammalian genome : official journal of the International Mammalian Genome Society · 2018Article
- The genomic ancestry, landscape genetics and invasion history of introduced mice in New Zealand.Royal Society open science · 2018Article
- Genetic vs environment influences on house mouse hybrid zone in Iran.Journal, genetic engineering & biotechnology · 2017Article
- Male Infertility Is Responsible for Nearly Half of the Extinction Observed in the Mouse Collaborative Cross.Genetics · 2017Article
- Genomes of the Mouse Collaborative Cross.Genetics · 2017Article
- CRISPR/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene.Scientific reports · 2017Article
- The Composite Regulatory Basis of the Large X-Effect in Mouse Speciation.Molecular biology and evolution · 2017Article
- Hybrid Sterility Locus on Chromosome X Controls Meiotic Recombination Rate in Mouse.PLoS genetics · 2016Article
- Gene regulation and speciation in house mice.Genome research · 2016Article
- The Founder Strains of the Collaborative Cross Express a Complex Combination of Advantageous and Deleterious Traits for Male Reproduction.G3 (Bethesda, Md.) · 2015Article
- A Cascade of epistatic interactions regulating teratozoospermia in mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2015Article
- Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hybrid breakdown is a type of reproductive failure that appears after the F2 generation of crosses between different species or subspecies. It is caused by incompatibility between interacting genes. Genetic analysis of hybrid breakdown, particularly in higher animals, has been hampered by its complex nature (i.e., it involves more than two genes, and the phenotype is recessive). We studied hybrid breakdown using a new consomic strain, C57BL/6J-X(MSM), in which the X chromosome of C57BL/6J (derived mostly from Mus musculus domesticus) is substituted by the X chromosome of the MSM/Ms strain (M. m. molossinus). Males of this consomic strain are sterile, whereas F1 hybrids between C57BL/6J and MSM/Ms are completely fertile. The C57BL/6J-X(MSM) males showed reduced testis weight with variable defects in spermatogenesis and abnormal sperm head morphology. We conducted quantitative trait locus (QTL) analysis for these traits to map the X-linked genetic factors responsible for the sterility. This analysis successfully detected at least three distinct loci for the sperm head morphology and one for the testis weight. This study revealed that incompatibility of interactions of X-linked gene(s) with autosomal and/or Y-linked gene(s) causes the hybrid breakdown between the genetically distant C57BL/6J and MSM/Ms strains.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.