ArticleGenetics2004
First-generation linkage map of the gray, short-tailed opossum, Monodelphis domestica, reveals genome-wide reduction in female recombination rates.
Article in Genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 57 citations in OpenAlex.
- Divergent 3D genome architecture of male germ cells across vertebrates.Nature communications · 2026Article
- Strategies for meiotic sex chromosome dynamics and telomeric elongation in Marsupials.PLoS genetics · 2022Article
- Genetic and genomic architecture in eight strains of the laboratory opossum Monodelphis domestica.G3 (Bethesda, Md.) · 2022Article
- Meiotic chromosome dynamics and double strand break formation in reptiles.Frontiers in cell and developmental biology · 2022Article
- Article
- High-resolution sex-specific linkage maps of the mouse reveal polarized distribution of crossovers in male germline.Genetics · 2014Article
- A microsatellite linkage map of striped bass (Morone saxatilis) reveals conserved synteny with the three-spined stickleback (Gasterosteus aculeatus).Marine biotechnology (New York, N.Y.) · 2012Article
- Article
- Review
- A second-generation anchored genetic linkage map of the tammar wallaby (Macropus eugenii).BMC genetics · 2011Article
- Genetic and evolutionary correlates of fine-scale recombination rate variation in Drosophila persimilis.Journal of molecular evolution · 2010Article
- Localization of genes for V+LDL plasma cholesterol levels on two diets in the opossum Monodelphis domestica.Journal of lipid research · 2010Article
- A comprehensive linkage map of the dog genome.Genetics · 2010Article
- American marsupials chromosomes: Why study them?Genetics and molecular biology · 2009Article
- Sex-specific differences in the synaptonemal complex in the genus Oreochromis (Cichlidae).Genetica · 2009Article
- A first-generation microsatellite-based genetic linkage map of the Siberian jay (Perisoreus infaustus): insights into avian genome evolution.BMC genomics · 2009Article
- A second generation genetic map for rainbow trout (Oncorhynchus mykiss).BMC genetics · 2008Article
- The opossum genome: insights and opportunities from an alternative mammal.Genome research · 2008Review
- Extreme heterochiasmy and nascent sex chromosomes in European tree frogs.Proceedings. Biological sciences · 2008Article
- Evolutionary dynamics of transposable elements in the short-tailed opossum Monodelphis domestica.Genome research · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
The gray, short-tailed opossum, Monodelphis domestica, is the most extensively used, laboratory-bred marsupial resource for basic biologic and biomedical research worldwide. To enhance the research utility of this species, we are building a linkage map, using both anonymous markers and functional gene loci, that will enable the localization of quantitative trait loci (QTL) and provide comparative information regarding the evolution of mammalian and other vertebrate genomes. The current map is composed of 83 loci distributed among eight autosomal linkage groups and the X chromosome. The autosomal linkage groups appear to encompass a very large portion of the genome, yet span a sex-average distance of only 633.0 cM, making this the most compact linkage map known among vertebrates. Most surprising, the male map is much larger than the female map (884.6 cM vs. 443.1 cM), a pattern contrary to that in eutherian mammals and other vertebrates. The finding of genome-wide reduction in female recombination in M. domestica, coupled with recombination data from two other, distantly related marsupial species, suggests that reduced female recombination might be a widespread metatherian attribute. We discuss possible explanations for reduced female recombination in marsupials as a consequence of the metatherian characteristic of determinate paternal X chromosome inactivation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.