Evidence map›Paper›PMID 15018132›Full record

ReviewRespirology (Carlton, Vic.)2003

SARS: prognosis, outcome and sequelae.

K S Chan, J P Zheng, Y W Mok, Y M Li, Y N Liu, C M Chu, M S Ip

3 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in Respirology (Carlton, Vic.), 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 137 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 7 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03274544 naterminatednot on this mapstarted 2018, after this paper: background citation

The Effectiveness of an Empirical Chinese Medicine Formulation for Idiopathic Pulmonary Fibrosis: an Open Label Clinical Trial

TypeinterventionalSponsorThe University of Hong KongRan2018 to 2020Enrolled6ConditionsIdiopathic Pulmonary FibrosisArmsPROLUNG
NCT04459351 unknown statusnot on this mapstarted 2020, after this paper: background citation

PHenotyping patiENts Admitted to Hospital With cOvid-19 Infection and idenTifYing Prognostic markErs

TypeobservationalSponsorChelsea and Westminster NHS Foundation TrustRan2020 to 2023Enrolled500ConditionsCoronavirus, Corona Virus Infection, COVID-19, 2019nCoV
NCT04952844 unknown statusnot on this mapstarted 2021, after this paper: background citation

Functional Capacity in Survivors of COVID-19 Related ARDS: A Cross-sectional Study

TypeobservationalSponsorKoç UniversityRan2021 to 2021Enrolled15ConditionsCovid19, Functional Capacity, Post-intensive Care Syndrome
3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 7 syntheses or guidelines pooled it, 267 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Guideline
  6. Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China.Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Pooled it
  7. Pooled it
  8. Trial
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Validation of a specialized evaluation system for COVID-19 in Japan: A retrospective, multicenter cohort study.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2023
    Article
  18. Screening and identification of potential MERS-CoV papain-like protease (PLpro) inhibitors; Steady-state kinetic and Molecular dynamic studies.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  19. Review
  20. Article

77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

K S ChanUnited Christian Hospital, Hong Kong, SAR, China. chanks@ha.org.hk
J P Zheng
Y W Mok
Y M Li
Y N Liu
C M Chu
M S Ip
State Key Laboratory of Respiratory Disease · CNUnited Christian Hospital · CNKowloon Hospital · CNUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome (SARS) is associated with considerable morbidity and mortality in the acute phase. Worldwide case fatality rate is 11% (range 7 to 27%) for the most severely affected regions. Several adverse prognostic factors have been identified, including advanced age, presence of comorbidity, higher lactose dehydrogenase levels and initial neutrophil count, but the impact of viral and other host factors on outcome is unknown. Published data on sequelae of SARS are limited. Clinical follow-up of patients who recovered from SARS has demonstrated radiological, functional and psychological abnormalities of varying degrees. In the early rehabilitation phase, many complained of limitations in physical function from general weakness and/or shortness of breath. In a small series of subjects who underwent CT scan of the chest, over half showed some patchy changes consistent with pulmonary fibrosis. Lung function testing at 6-8 weeks after hospital discharge showed mild or moderate restrictive pattern consistent with muscle weakness in 6-20% of subjects. Mild decrease in carbon monoxide diffusing capacity was detected in a minority of subjects. Preliminary evidence suggests that these lung function abnormalities will improve over time. Psychobehavioural problems of anxiety and/or depression were not uncommon in the early recovery phase, and improved over time in the majority of patients. Avascular necrosis of the hip has been reported as another complication. The long-term sequelae of SARS are still largely unknown. It is important to follow up these patients to detect and appropriately manage any persistent or emerging long-term sequelae in the physical, psychological and social domains.

Indexed as

Severe Acute Respiratory SyndromeHumansLung DiseasesPrognosisTreatment Outcome

Identifiers

PMID15018132
PMCPMC7169213
OpenAlexW1970860163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.