ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2004
Pharmacokinetic and pharmacodynamic issues in the treatment of bacterial infectious diseases.
Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Solving the degradation problem of continuous ceftazidime infusions-the Cooltaz study.Antimicrobial agents and chemotherapy · 2026Article
- Synthesis, characterization, crystal engineering, DFT, and biological evaluation of a novel Cu(II)-perchlorate Schiff base complex.BMC chemistry · 2025Article
- PK/PD-Guided Strategies for Appropriate Antibiotic Use in the Era of Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2025Review
- SMI-Capsular Fibrosis and Biofilm Dynamics: Molecular Mechanisms, Clinical Implications, and Antimicrobial Approaches.International journal of molecular sciences · 2024Review
- Clinical Challenge: Standard Versus Extended Meropenem Infusion in Children.Turkish archives of pediatrics · 2024Article
- Use of Antimicrobial Irrigation and Incidence of Capsular Contracture in Breast Augmentation and Immediate Implant-Based Breast Reconstruction.Aesthetic plastic surgery · 2023Review
- Pharmacokinetic assessment of cefpodoxime proxetil in diabetic rats.Journal of diabetes and metabolic disorders · 2023Article
- Determination of biological activities of nanoparticles containing silver and copper in water disinfection with/without ultrasound technique.Journal of environmental health science & engineering · 2023Article
- Ways to Improve Insights into Clindamycin Pharmacology and Pharmacokinetics Tailored to Practice.Antibiotics (Basel, Switzerland) · 2022Review
- Identification of Novel and Safe Fungicidal Molecules againstBioMed research international · 2022Article
- Improving intraoperative administration of surgical antimicrobial prophylaxis: a quality improvement report.BMJ open quality · 2020Article
- The art and science of drug titration.Therapeutic advances in drug safety · 2020Review
- Antimicrobial Irrigation and Technique during Breast Augmentation: Survey of Current Practice.Plastic and reconstructive surgery. Global open · 2019Article
- Assessment of vancomycin utilization among Lebanese hospitals.Saudi medical journal · 2019Article
- Widely Used Benzalkonium Chloride Disinfectants Can Promote Antibiotic Resistance.Applied and environmental microbiology · 2018Article
- An in vitro proof-of-principle study of sonobactericide.Scientific reports · 2018Article
- Pharmacokinetics of ceftiofur in healthy and lipopolysaccharide-induced endotoxemic newborn calves treated with single and combined therapy.The Journal of veterinary medical science · 2017Article
- Review
- Local Intramedullary Delivery of Vancomycin Can Prevent the Development of Long Bone Staphylococcus aureus Infection.PloS one · 2016Article
- Exploring the collaboration between antibiotics and the immune response in the treatment of acute, self-limiting infections.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review outlines some of the many factors a clinician must consider when selecting an antimicrobial dosing regimen for the treatment of infection. Integration of the principles of antimicrobial pharmacology and the pharmacokinetic parameters of an individual patient provides the most comprehensive assessment of the interactions between pathogen, host, and antibiotic. For each class of agent, appreciation of the different approaches to maximize microbial killing will allow for optimal clinical efficacy and reduction in risk of development of resistance while avoiding excessive exposure and minimizing risk of toxicity. Disease states with special considerations for antimicrobial use are reviewed, as are situations in which pathophysiologic changes may alter the pharmacokinetic handling of antimicrobial agents.
Indexed as
Identifiers
15015030What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.