ArticleThe Journal of membrane biology1992
Single-membrane and cell-to-cell permeability properties of dissociated embryonic chick lens cells.
Article in The Journal of membrane biology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Properties of connexin 46 hemichannels in dissociated lens fiber cells.Investigative ophthalmology & visual science · 2011Article
- The lens circulation.The Journal of membrane biology · 2007Review
- The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells.The Journal of cell biology · 1997Article
- Switch in gap junction protein expression is associated with selective changes in junctional permeability during keratinocyte differentiation.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Double whole-cell patch-clamp characterization of gap junctional channels in isolated insect epidermal cell pairs.The Journal of membrane biology · 1993Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Ion channels are believed to play an important role in the maintenance of lens transparency. In order to ascribe junctional and nonjunctional permeability properties to specific lens cell types, embryonic chick lenses were enzymatically dissociated into cell clusters, cell pairs and single cells, and both cell-to-cell and single-membrane permeability properties were characterized with the patch-clamp technique. Double patch-clamp experiments and single patch-clamp experiments with Lucifer yellow in the pipette demonstrated that the cells in the dissociated preparation were well coupled, the average conductance between pairs being 42 +/- 27 nS. Double patch-clamp experiments also revealed single cell-to-cell channel events with a predominant unitary conductance of 286 +/- 38 pS. Whole-cell measurements of surface membrane conductance indicate heterogeneity within the population of dissociated embryonic chick lens cells: 63% of the cells have a voltage-independent leak current, 14% of the cells have a potassium-selective inward-rectifier current, and 23% of the cells have a current which turns off with positive voltage on a time scale on the order of seconds. The time constant for this turnoff is voltage dependent.
Indexed as
Identifiers
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Registered trials
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