ArticlePlant molecular biology2003
Rapid induction of a protein disulfide isomerase and defense-related genes in wheat in response to the hemibiotrophic fungal pathogen Mycosphaerella graminicola.
Article in Plant molecular biology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44 citing papers in PubMed, 121 citations in OpenAlex.
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- Stomatal penetration: the cornerstone of plant resistance to the fungal pathogen Zymoseptoria tritici.BMC plant biology · 2024Article
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- Comparison of the impact of two key fungal signalling pathways on Zymoseptoria tritici infection reveals divergent contribution to invasive growth through distinct regulation of infection-associated genes.Molecular plant pathology · 2023Article
- Characterization and functional analyses of wheat TaPR1 genes in response to stripe rust fungal infection.Scientific reports · 2023Article
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- An interolog-based barley interactome as an integration framework for immune signaling.Genetics · 2022Article
- Coordinated regulation of plant immunity by poly(ADP-ribosyl)ation and K63-linked ubiquitination.Molecular plant · 2021Article
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- Proteome Changes in Stem Tissues of Sunflower Lines Inoculated with Culture Filtrate ofIranian journal of biotechnology · 2021Article
- Identification of QTLs for Resistance toGenes · 2020Article
- A TMT-Based Quantitative Proteome Analysis to Elucidate the TSWV Induced Signaling Cascade in Susceptible and Resistant Cultivars ofPlants (Basel, Switzerland) · 2020Article
- Taxonomically Restricted Wheat Genes Interact With Small Secreted Fungal Proteins and Enhance Resistance to Septoria Tritici Blotch Disease.Frontiers in plant science · 2020Article
- The biotrophy-associated secreted protein 4 (BAS4) participates in the transition ofSaudi journal of biological sciences · 2019Article
- Highly flexible infection programs in a specialized wheat pathogen.Ecology and evolution · 2019Article
- A Review of the Interactions between Wheat and Wheat Pathogens: Zymoseptoria tritici, Fusarium spp. and Parastagonospora nodorum.International journal of molecular sciences · 2018Review
- A role for random, humidity-dependent epiphytic growth prior to invasion of wheat by Zymoseptoria tritici.Fungal genetics and biology : FG & B · 2017Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mycosphaerella graminicola, incitant of septoria tritici blotch, is a widespread and significant pathogen of wheat that is not closely related to other fungi being developed as genetic models for host-pathogen interactions. Several resistance genes in wheat have been identified, yet the molecular mechanisms of resistance are unknown. To identify host genes involved in the resistance response, expression profiles of the wheat line Tadinia (containing the Stb4 gene for resistance) and the susceptible line Yecora Rojo, non-inoculated or inoculated with M. graminicola, were compared by differential-display polymerase chain reaction (DD-PCR). Among the differentially expressed genes was a protein disulfide isomerase (PDI), which is well known as a molecular chaperone and component of signal-transduction pathways in animal systems but had not been implicated previously in plant defense response. Real-time quantitative reverse-transcription PCR and northern analysis revealed that PDI was induced within 3 h of inoculation with highest induction in the pathogen-treated resistant lines. These responses of PDI were similar to the early and strong resistance-related responses displayed by the pathogenesis-related (PR) proteins, PR-1, PR-2 and PR-5. In contrast, a wheat lipoxygenase was down-regulated in the resistant lines at time points corresponding with peak induction of the PR genes. Thus, part of the resistance mechanism may involve repression of a gene that could otherwise aid fungal growth. Wheat responds much more rapidly than believed previously to signals produced by M.graminicola. These early responses begin prior to penetration of the host and appear to determine the outcome of the host-pathogen interaction.
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