Evidence map›Paper›PMID 15007636›Full record

ReviewSpringer seminars in immunopathology2004

Immunological mechanisms in specific immunotherapy.

Carsten B Schmidt-Weber, Kurt Blaser

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Springer seminars in immunopathology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

  1. Probiotics and Atopic Dermatitis: An Overview.Frontiers in microbiology · 2016
    Review
  2. Stress and allergic diseases.Immunology and allergy clinics of North America · 2011
    Review
  3. Oral immunotherapy for food allergy.Current allergy and asthma reports · 2009
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carsten B Schmidt-WeberSwiss Institute of Allergy and Asthma Research, Davos, Switzerland. csweber@siaf.unizh.ch
Kurt Blaser

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specific immunotherapy (SIT) represents the only curative treatment of allergy and is, therefore, of particular interest for immunological and pharmacological research. The current understanding of immunological mechanisms underlying SIT focuses on regulatory T cells (T regs), which balance Th1 and Th2 effector functions. This ensures that allergens are recognized, but tolerated by the immune system. There is clear evidence that SIT restores the disturbed balance of T regs and effector cells in allergic patients. Current efforts are focused to improve SIT regimens to make them more applicable in atopy and asthma. The current review provides an overview on the mechanisms of SIT and possible adjuvant treatment strategies on the background of the T reg concept.

Indexed as

AnimalsAsthmaHumansHypersensitivityImmunotherapyT-Lymphocytes

Identifiers

PMID15007636
OpenAlexW2066138537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.