ArticleApplied and environmental microbiology2004
L-alanine auxotrophy of Lactobacillus johnsonii as demonstrated by physiological, genomic, and gene complementation approaches.
Article in Applied and environmental microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Strain-resolved biology ofFrontiers in veterinary science · 2026Review
- Insights into host dependency from a chemically defined medium for the human vaginal bacterium Lactobacillus crispatus.Archives of microbiology · 2025Article
- Taxonomic and environmental distribution of bacterial amino acid auxotrophies.Nature communications · 2023Article
- Genome-Based Metabolic Reconstruction Unravels the Key Role of B12 in Methionine Auxotrophy of anFrontiers in microbiology · 2019Article
- Emerging Role of D-Amino Acid Metabolism in the Innate Defense.Frontiers in microbiology · 2018Review
- Interplay between microbial d-amino acids and host d-amino acid oxidase modifies murine mucosal defence and gut microbiota.Nature microbiology · 2016Article
- H(2)O(2) production in species of the Lactobacillus acidophilus group: a central role for a novel NADH-dependent flavin reductase.Applied and environmental microbiology · 2014Article
- Article
- Identification of genes associated with the long-gut-persistence phenotype of the probiotic Lactobacillus johnsonii strain NCC533 using a combination of genomics and transcriptome analysis.Journal of bacteriology · 2008Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using a chemically defined medium without L-alanine, Lactobacillus johnsonii was demonstrated to be strictly auxotrophic for that amino acid. A comparative genetic analysis showed that all known genes involved in L-alanine biosynthesis are absent from the genome of L. johnsonii. This auxotrophy was complemented by heterologous expression of the Bacillus subtilis L-alanine dehydrogenase.
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Registered trials
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