Evidence map›Paper›PMID 15004685›Full record

ReviewHNO2004

[HPV-associated tonsillar cancer. An update].

J P Klussmann, S Dinh, O Guntinas-Lichius, C Wittekindt, S Weissenborn, U Wieland, H P Dienes, T Hoffmann, E Smith, L Turek and 2 more

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in HNO, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Basics of tumor development and importance of human papilloma virus (HPV) for head and neck cancer.GMS current topics in otorhinolaryngology, head and neck surgery · 2012
    Article
  6. Review
  7. Review
  8. Review
  9. [Impact of prophylactic HPV vaccines on dermatology and venereology].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2007
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

J P KlussmannKlinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde des Klinikum der Universität zu Köln, Cologne. peter.klussmann@uni-koeln.de
S Dinh
O Guntinas-Lichius
C Wittekindt
S Weissenborn
U Wieland
H P Dienes
T Hoffmann
E Smith
L Turek
E J M Speel
H J Pfister
University of Cologne · DEKlinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde · DEUniversity of Iowa · USMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The major risk factors for head and neck squamous cell carcinomas (HNSCC) are considered to be tobacco and alcohol. A link between oncogenic types of the human papilloma virus (HPV) and the risk of HNSCC has been suggested in the literature. However, the causal link is now becoming more firmly established on the basis of recent analyses. About 20% of all HNSCC and more than 50% of tonsillar cancers contain HR-HPV. The causal role of HPV-infection in carcinogenesis and the molecular mechanisms involved could thus far be best elucidated in the case of cervical carcinomas. New insights and increasing evidence for the analogy of HPV-positive HNSCC with cervical cancer are discussed. The definition of HPV-positive HNSCC has become more important due to the implications for risk factors and prognosis.

Indexed as

Alcohol DrinkingCarcinoma, Squamous CellCell Transformation, NeoplasticDNA Probes, HPVHumansPalatine TonsilPapillomaviridaePapillomavirus InfectionsPrognosisRisk FactorsSmokingTonsillar NeoplasmsVirulenceDNA Probes, HPV

Identifiers

PMID15004685
OpenAlexW2421011551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.