Evidence map›Paper›PMID 15004115›Full record

ArticleJournal of clinical microbiology2004

Highly conserved alpha-toxin sequences of avian isolates of Clostridium perfringens.

Scott A Sheedy, Aaron B Ingham, Julian I Rood, Robert J Moore

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. A lytic bacteriophage isolate reducedFrontiers in veterinary science · 2022
    Article
  4. Article
  5. Protein Truncating Variants ofFrontiers in cellular and infection microbiology · 2021
    Article
  6. Article
  7. Two putative zinc metalloproteases contribute to the virulence ofJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020
    Article
  8. Genotyping ofBioMed research international · 2020
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Scott A SheedyCommonwealth Scientific and Industrial Research Organisation, Livestock Industries, Australian Animal Health Laboratory, Geelong 3220, Australia.
Aaron B Ingham
Julian I Rood
Robert J Moore

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clostridium perfringens causes necrotic enteritis in chickens, and alpha-toxin has been suggested to be a key virulence determinant. Analysis of the alpha-toxin of 25 chicken-derived C. perfringens strains demonstrated high homology to mammal-derived strains rather than to the only avian-derived C. perfringens alpha-toxin sequence reported previously.

Indexed as

Calcium-Binding ProteinsAmino Acid SequenceAnimalsAustraliaBacterial ToxinsBase SequenceChickensClostridium InfectionsClostridium perfringensConserved SequenceDNA PrimersHumansIntestinal MucosaMolecular Sequence DataPolymerase Chain ReactionPoultry Diseasesalpha toxin, Clostridium perfringensBacterial ToxinsCalcium-Binding ProteinsDNA PrimersType C Phospholipases

Identifiers

PMID15004115
PMCPMC356866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.