Evidence map›Paper›PMID 15000526›Full record

ArticleJournal of bioenergetics and biomembranes2003

Nonchannel functions of the calcium channel gamma subunit: insight from research on the stargazer mutant.

Xiaoxi Qiao, Hongdi Meng

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of bioenergetics and biomembranes, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Calcium channels: unanswered questions.Journal of bioenergetics and biomembranes · 2003
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xiaoxi QiaoDepartment of Cellular Biology & Anatomy, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, Louisiana 71130, USA. xqiao@lsuhsc.edu
Hongdi Meng
Louisiana State University Health Sciences Center Shreveport · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Voltage-dependent calcium channels (VDCC) are essential regulators of intracellular calcium concentration, which in turn influences a broad spectrum of cellular functions especially in neurons. Identification of several calcium channel mutations as the cause of neurological disorders in human and mouse indicates the importance of the integrity of these channels to neuronal function. Studies of mutant mice, each carrying a disrupted gene of a different VDCC subunit, have revealed many unexpected roles of these molecules and have significantly advanced our knowledge of subunit function in the last few years. This review addresses recent discoveries of the function of the gamma2 subunit, also named stargazin, with special emphasis on roles other than calcium conductance.

Indexed as

Amino Acid SequenceAmino Acid SubstitutionAnimalsBrain-Derived Neurotrophic FactorCalcium Channelsgamma-Aminobutyric AcidGene Expression RegulationHumansMembrane PotentialsMiceMolecular Sequence DataNeuronsProtein BindingProtein ConformationReceptors, AMPASequence Homology, Amino AcidBrain-Derived Neurotrophic FactorCACNG2 protein, humanCacng2 protein, mouseCalcium Channelsgamma-Aminobutyric AcidReceptors, AMPA

Identifiers

PMID15000526
OpenAlexW1983772170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.