Evidence map›Paper›PMID 15000516›Full record

ReviewJournal of bioenergetics and biomembranes2003

Calcium channels: unanswered questions.

Stephen W Jones

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of bioenergetics and biomembranes, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Ca(2+) signaling by T-type Ca(2+) channels in neurons.Pflugers Archiv : European journal of physiology · 2009
    Review
  8. Article
  9. Spike propagation in dendrites with stochastic ion channels.Journal of computational neuroscience · 2006
    Article
  10. A short history of voltage-gated calcium channels.British journal of pharmacology · 2006
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Stephen W JonesDepartment of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio 44106, USA. swj@cwru.edu

Funding

PEPTIDE ACTION IN AUTONOMIC GANGLIAR01NS024471 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI JONES, STEPHEN W · 1986 to 2007
$2.0M
NINDS NIH HHS NS24471
6 · The paper itself

Abstract

Despite decades of intensive research, many questions remain unresolved regarding the structure and function of voltage-dependent calcium channels. This review considers some of those questions: Where is the activation gate? Where are the inactivation gates? How are the voltage sensors coupled to the gates? Are bacterial K+ channels good models for the Ca2+ channel pore? Are protein-protein interactions fundamental to Ca2+ channel function? Do voltage-dependent Ca2+ channels regulate basal intracellular Ca2+? Are N and P/Q channels specialized for fast neurotransmitter release?

Indexed as

Amino Acid SequenceAnimalsCalciumCalcium ChannelsCalcium SignalingCell Membrane PermeabilityHomeostasisHumansIon Channel GatingMembrane PotentialsMolecular Sequence DataPorosityStructure-Activity RelationshipCalciumCalcium Channels

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.