Evidence map›Paper›PMID 14994762›Full record

ArticleThe Annals of otology, rhinology, and laryngology2004

Anatomy and fiber type composition of human interarytenoid muscle.

Cari M Tellis, Clark Rosen, Apurva Thekdi, James J Sciote

Abstract read
In one paragraph

Article in The Annals of otology, rhinology, and laryngology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 56 citations in OpenAlex.

  1. Laryngeal muscle responses to mechanical displacement of the thyroid cartilage in humans.Journal of applied physiology (Bethesda, Md. : 1985) · 2005
    Trial
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  11. Central nervous system control of the laryngeal muscles in humans.Respiratory physiology & neurobiology · 2005
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cari M TellisDepartment of Communication Science and Disorders, University of Pittsburgh, Pennsylvania, USA.
Clark Rosen
Apurva Thekdi
James J Sciote
University of Pittsburgh · US

Funding

Functional &Molecular Study of Human Laryngeal MusclesR01DC005058 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCIOTE, JAMES J · 2002 to 2004
$841k
NIDCD NIH HHS R01 DC005058
6 · The paper itself

Abstract

Intrinsic laryngeal muscle investigations, especially those of the interarytenoid (IA) muscle, have been primarily teleologically based. We determined IA muscle anatomy and histochemical and immunohistochemical classification of extrafusal and intrafusal (muscle spindle) fibers in 5 patients. Extrafusal fibers were oxidative type I and glycolytic types IIA and IIX. Intrafusal fibers of muscle spindles were identified by the presence of tonic and neonatal myosin. The results demonstrate that the IA muscle has a phenotype similar to that of limb skeletal muscle. Myosin coexpression, the absence of intrafusal fibers, and fiber type grouping were unusual features found previously in the thyroarytenoid and posterior cricoarytenoid muscles, but they were not present in the IA muscle. These findings lead to the conclusion that the IA muscle has functional significance beyond its assumed importance in maintaining vocal fold position during phonation. The presence of spindles demonstrates differences in motor control as compared to the thyroarytenoid and posterior cricoarytenoid muscles. Further, extrafusal fiber characteristics implicate IA muscle involvement in muscle tension dysphonia and adductor spasmodic dysphonia. Given the unique physiologic characteristics of the human IA muscle, further research into the role of the IA muscle in voice disorders is warranted.

Indexed as

Adenosine TriphosphateAgedAntibodiesArytenoid CartilageCarbohydrate DehydrogenasesFemaleGlycerol-3-Phosphate Dehydrogenase (NAD+)Glycerolphosphate DehydrogenaseHumansImmunohistochemistryLaryngeal MusclesMaleMuscle Fibers, SkeletalMuscle SpindlesMyofibrilsMyosin Heavy ChainsAdenosine TriphosphateAntibodiesCarbohydrate DehydrogenasesGlycerol-3-Phosphate Dehydrogenase (NAD+)Glycerolphosphate DehydrogenaseMyosin Heavy Chainssorbose dehydrogenase

Identifiers

PMID14994762
PMCPMC3860318
OpenAlexW2031739912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.