ArticleBiophysical journal2004
Electric field-driven transformations of a supported model biological membrane--an electrochemical and neutron reflectivity study.
Article in Biophysical journal, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- A Spectroelectrochemical Study of the Effect of Asymmetry on the Electrochemical Response of Lipid Bilayers.The journal of physical chemistry. B · 2026Article
- Monitoring of Bicelles Spreading into Floating Lipid Bilayers.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Effect of Anionic Lipids on Mammalian Plasma Cell Membrane Properties.Langmuir : the ACS journal of surfaces and colloids · 2023Article
- Influence of the Lipid Backbone on Electrochemical Phase Behavior.Langmuir : the ACS journal of surfaces and colloids · 2022Article
- Designing a Useful Lipid Raft Model Membrane for Electrochemical and Surface Analytical Studies.Molecules (Basel, Switzerland) · 2021Article
- Protective Role of Sphingomyelin in Eye Lens Cell Membrane Model against Oxidative Stress.Biomolecules · 2021Article
- A combination of electrochemistry and mass spectrometry to monitor the interaction of reactive species with supported lipid bilayers.Scientific reports · 2020Article
- Alzheimer's disease-related amyloid β peptide causes structural disordering of lipids and changes the electric properties of a floating bilayer lipid membrane.Nanoscale advances · 2020Article
- Understanding dynamic changes in live cell adhesion with neutron reflectometry.Modern physics letters. B, Condensed matter physics, statistical physics, applied physics · 2014Article
- Modulation of electrochemical hydrogen evolution rate by araliphatic thiol monolayers on gold.Electrochimica acta · 2013Article
- Adhesion signals of phospholipid vesicles at an electrified interface.The Journal of membrane biology · 2012Article
- Neural Stem Cell Spreading on Lipid Based Artificial Cell Surfaces, Characterized by Combined X-ray and Neutron Reflectometry.Materials (Basel, Switzerland) · 2010Article
- Mouse fibroblast cell adhesion studied by neutron reflectometry.Biophysical journal · 2010Article
- Biophysical effects of electric fields on membrane water interfaces: a mini review.European biophysics journal : EBJ · 2007Review
- Effect of an electric field on a floating lipid bilayer: A neutron reflectivity study.The European physical journal. E, Soft matter · 2006Article
- Electric field unbinding of solid-supported lipid multilayers.The European physical journal. E, Soft matter · 2005Article
- Electrochemical and PM-IRRAS studies of the effect of cholesterol on the structure of a DMPC bilayer supported at an Au (111) electrode surface, part 1: properties of the acyl chains.Biophysical journal · 2005Article
- Electrochemical and photon polarization modulation infrared reflection absorption spectroscopy study of the electric field driven transformations of a phospholipid bilayer supported at a gold electrode surface.Biophysical journal · 2003Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A mixed bilayer of cholesterol and dimyristoylphosphatidylcholine has been formed on a gold-coated block of quartz by fusion of small unilamellar vesicles. The formation of this bilayer lipid membrane on a conductive surface allowed us to study the influence of the support's surface charge on the structure and hydration of the bilayer lipid membrane. We have employed electrochemical measurements and the specular reflection of neutrons to measure the thickness and water content in the bilayer lipid membrane as a function of the charge on the support's surface. When the surface charge density is close to zero, the lipid vesicles fuse directly on the surface to form a bilayer with a small number of defects and hence small water content. When the support's surface is negatively charged the film swells and incorporates water. When the charge density is more negative than -8 micro C cm(-2), the bilayer starts to detach from the metal surface. However, it remains in a close proximity to the metal electrode, being suspended on a thin cushion of the electrolyte. The field-driven transformations of the bilayer lead to significant changes in the film thicknesses. At charge densities more negative than -20 micro C cm(-2), the bilayer is approximately 37 A thick and this number is comparable to the thickness determined for hydrated multilayers of dimyristoylphosphatidylcholine from x-ray diffraction experiments. The thickness of the bilayer decreases at smaller charge densities to become equal to approximately 26 A at zero charge. This result indicates that the tilt of the acyl chains with respect to the bilayer normal changes from approximately 35 degrees to 59 degrees by moving from high negative charges (and potentials) to zero charge on the metal.
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