ReviewClinical microbiology reviews1992
Molecular and immunological diagnosis of echinococcosis.
Review in Clinical microbiology reviews, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 132 citations in OpenAlex.
- The technical aspects of ex vivo hepatectomy with autotransplantation: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2021Pooled it
- Diagnostic Pathways and Genotyping of Cases ofPathogens (Basel, Switzerland) · 2026Article
- The diagnosis and pathology of cystic echinococcosis of the bone: a description of two cases.Quantitative imaging in medicine and surgery · 2025Article
- Preliminary Evaluation of Recombinant EPC1 and TPx for Serological Diagnosis of Animal Cystic Echinococcosis.Frontiers in cellular and infection microbiology · 2020Article
- A rare case of the simultaneous location of Echinococcus multilocularis in the liver and the head of the pancreas: case report analysis and review of literature.BMC infectious diseases · 2019Article
- A new treatment strategy for end-stage hepatic alveolar echinococcosis: IVC resection without reconstruction.Scientific reports · 2019Article
- Article
- Alveolar hydatid disease of the liver: A rare entity in India.Medical journal, Armed Forces India · 2016Article
- Current status of diagnosis and treatment of hepatic echinococcosis.World journal of hepatology · 2016Review
- Evaluation of purified antigen fraction in the immunodiagnosis of cystic echinococcosis.Parasitology research · 2014Article
- Performance of polymerase chain reaction for the diagnosis of cystic echinococcosis using serum, urine, and cyst fluid samples.Tropical parasitology · 2014Article
- Differential diagnosis of cystic and alveolar echinococcosis using an immunochromatographic test based on the detection of specific antibodies.Parasitology research · 2013Article
- Zoonotic infections in Alaska: disease prevalence, potential impact of climate change and recommended actions for earlier disease detection, research, prevention and control.International journal of circumpolar health · 2013Article
- Hepatic echinococcosis: clinical and therapeutic aspects.World journal of gastroenterology · 2012Review
- Immunochromatographic test with recombinant Em18 antigen for the follow-up study of alveolar echinococcosis.Clinical and vaccine immunology : CVI · 2011Article
- Molecular characterization of antigen B2 subunit in two genotypes of Echinococcus granulosus from Indian bubaline isolates, its stage specific expression and serological evaluation.Molecular biology reports · 2011Article
- Serodiagnosis of Echinococcus spp. infection: explorative selection of diagnostic antigens by peptide microarray.PLoS neglected tropical diseases · 2010Article
- Evaluation of two ELISA and two indirect hemagglutination tests for serodiagnosis of pulmonary hydatid disease.The Korean journal of parasitology · 2009Article
- Differential diagnosis and management of a recurrent hepatic cyst: a case report and review of literature.Journal of general internal medicine · 2009Review
- Diagnosis of parasitic diseases: old and new approaches.Interdisciplinary perspectives on infectious diseases · 2009Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Echinococcosis is an infectious disease of humans caused by the larval (metacestode) stage of the cestode species Echinococcus granulosus (cystic echinococcosis or hydatid disease) or Echinococcus multilocularis (alveolar echinococcosis or alveolar hydatid disease). Clinical manifestations depend primarily on localization and size of hepatic lesions and may include hepatomegaly, obstructive jaundice, or cholangitis. Prognostically, alveolar echinococcosis is considered similar to liver malignancies, including a lethality rate of 90% for untreated cases. Diagnosis is based on imaging techniques coupled with immunodiagnostic procedures. Antibody detection tests for E. multilocularis have markedly improved with the use of affinity-purified Em2 antigen and recombinant antigen II/3-10 in enzyme immunoassays. Antigens of corresponding quality for E. granulosus are still unavailable. The detection of circulating antigens and immune complexes in the sera of patients with cystic echinococcosis, the demonstration of in vitro lymphocyte proliferation in response to stimulation with Echinococcus antigens, and the discrimination of serum immunoglobulin isotype activity to various Echinococcus antigens in both cystic and alveolar echinococcosis have been suggested for diagnostic purposes as well as for monitoring patients after treatment. New diagnostic molecular tools include DNA probes for Southern hybridization tests and polymerase chain reaction for the amplification of E. multilocularis and E. granulosus species-specific DNA fragments.
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