ReviewJournal of mammary gland biology and neoplasia2003
Wnt-cadherin connections in normal and neoplastic mammary epithelium.
Review in Journal of mammary gland biology and neoplasia, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 22 citations in OpenAlex.
- Notch3 Knockout Suppresses Mouse Mammary Gland Development and Inhibits the Proliferation of 4T1 Murine Mammary Carcinoma Cells via CCL2/CCR4 Axis.Frontiers in cell and developmental biology · 2020Article
- Progesterone decreases levels of the adhesion protein E-cadherin and promotes invasiveness of steroid receptor positive breast cancers.Hormones & cancer · 2013Article
- Transgenic models to study actions of prolactin in mammary neoplasia.Journal of mammary gland biology and neoplasia · 2008Review
- The molecular culprits underlying precocious mammary gland involution.Journal of mammary gland biology and neoplasia · 2007Review
- Survival of mammary stem cells in suspension culture: implications for stem cell biology and neoplasia.Journal of mammary gland biology and neoplasia · 2005Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the early recognition that the murine Wnt locus is frequently activated by insertion of the mouse mammary tumour virus, the Wnt pathway has become increasingly associated with both normal and abnormal mammary gland development. This link is further underlined by an emerging role for Wnt deregulation in human mammary neoplasia. The control of transcription through the Wnt signaling pathway is clearly a prime element of this role; however, components of the Wnt pathway possess many functions in addition to their signaling activity, interacting with multiple factors implicated in cellular control processes. Prominent amongst these are the cadherins, which have characterized roles in mediating cell-cell adhesion, and which have been independently implicated in mammary neoplasia. The close interplay between these 2 systems will be discussed in this review with reference both to the normal development of the mammary gland and to the onset of neoplasia in this tissue.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.