ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2004
Monitoring clathrin-mediated endocytosis during synaptic activity.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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Who cites it
26 citing papers in PubMed, 58 citations in OpenAlex.
- CAST/ELKS-endophilin-A interaction ensures synaptic vesicle pool size.The Journal of cell biology · 2026Article
- Article
- Deployment of endocytic machinery to periactive zones of nerve terminals is independent of active zone assembly and evoked release.bioRxiv : the preprint server for biology · 2026Article
- Clathrin packets move in slow axonal transport and deliver functional payloads to synapses.Neuron · 2021Article
- Article
- The Active and Periactive Zone Organization and the Functional Properties of Small and Large Synapses.Frontiers in synaptic neuroscience · 2016Article
- Differential targeting of dynamin-1 and dynamin-3 to nerve terminals during chronic suppression of neuronal activity.Molecular and cellular neurosciences · 2015Article
- Synaptic vesicles are "primed" for fast clathrin-mediated endocytosis at the ribbon synapse.Frontiers in molecular neuroscience · 2014Article
- The reserve pool of synaptic vesicles acts as a buffer for proteins involved in synaptic vesicle recycling.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Soluble membrane trafficking proteins taking a break at silent synaptic vesicles.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- A readily retrievable pool of synaptic vesicles.Nature neuroscience · 2011Article
- Bicaudal-D binds clathrin heavy chain to promote its transport and augments synaptic vesicle recycling.The EMBO journal · 2010Article
- Sharing vesicles between central presynaptic terminals: implications for synaptic function.Frontiers in synaptic neuroscience · 2010Article
- Actin and dynamin recruitment and the lack thereof at exo- and endocytotic sites in PC12 cells.Pflugers Archiv : European journal of physiology · 2009Article
- The dynamic control of kiss-and-run and vesicular reuse probed with single nanoparticles.Science (New York, N.Y.) · 2009Article
- Calcyon is necessary for activity-dependent AMPA receptor internalization and LTD in CA1 neurons of hippocampus.The European journal of neuroscience · 2009Article
- Synaptic vesicle endocytosis: fast and slow modes of membrane retrieval.Trends in neurosciences · 2008Review
- Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2.The Journal of cell biology · 2007Article
- Quantum dots provide an optical signal specific to full collapse fusion of synaptic vesicles.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Molecular dynamics of a presynaptic active zone protein studied in Munc13-1-enhanced yellow fluorescent protein knock-in mutant mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To visualize clathrin redistribution during endocytosis in hippocampal boutons, we used a fusion protein of clathrin light chain with enhanced green fluorescent protein. Both high potassium and electric field stimulation lead after a stimulus-dependent delay to a transient increase of fluorescence in synapses, but a slight and transient decrease in adjacent axonal segments. We conclude that the rise and fall of the signal in boutons, with decay kinetics remarkably similar to previous estimates of the endocytic time course, reflects coat assembly and disassembly. Thus, we could selectively measure clathrin-mediated endocytosis and separate its kinetics from other modes of membrane retrieval in CNS synapses. A long-lasting delay preceding the fluorescent transients shows that endocytosis during the first few seconds of continuing stimulation cannot be mediated by newly formed clathrin-coated pits. Therefore, a fast mode of endocytosis is either clathrin-independent or involves preassembled (easily retrievable) clathrin lattices at sites of endocytosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.