Evidence map›Paper›PMID 14982811›Full record

ArticleAntimicrobial agents and chemotherapy2004

Activities of dalbavancin in vitro and in a rabbit model of experimental endocarditis due to Staphylococcus aureus with or without reduced susceptibility to vancomycin and teicoplanin.

Agnès Lefort, Juliette Pavie, Louis Garry, Françoise Chau, Bruno Fantin

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Dalbavancin (zeven), a novel glycopeptide for resistant gram-positive organisms.P & T : a peer-reviewed journal for formulary management · 2008
    Article
  12. Dalbavancin.Drugs · 2008
    Review
  13. Article
  14. Antipneumococcal activity of dalbavancin compared to other agents.Antimicrobial agents and chemotherapy · 2005
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Agnès LefortFaculté de Médecine Xavier Bichat and University Paris VII, 75018 Paris, France. aglefort@yahoo.com
Juliette Pavie
Louis Garry
Françoise Chau
Bruno Fantin
Université Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For the treatment of rabbit endocarditis, dalbavancin given once daily (10 mg/kg of body weight for 4 days) or as a single 40-mg/kg dose was active against Staphylococcus aureus with or without reduced susceptibility to glycopeptides, as expected from its good in vitro activity, even in broth supplemented with 90% serum and given its prolonged elimination half-life.

Indexed as

Vancomycin ResistanceAnimalsArea Under CurveColony Count, MicrobialDrug Resistance, BacterialEndocarditis, BacterialFemaleGlycopeptidesHalf-LifeRabbitsStaphylococcal InfectionsTeicoplanindalbavancinGlycopeptidesTeicoplanin

Identifiers

PMID14982811
PMCPMC353077
OpenAlexW1975045523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.