ReviewJournal of neurovirology2004
Human immunodeficiency virus type 1 compartmentalization in the central nervous system.
Review in Journal of neurovirology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 45 citations in OpenAlex.
- Review
- HIV-1 Envelope Protein gp120 Promotes Proliferation and the Activation of Glycolysis in Glioma Cell.Cancers · 2018Article
- Applications of the FIV Model to Study HIV Pathogenesis.Viruses · 2018Review
- Genetic analyses of HIV env associated with uveitis in antiretroviral-naive individuals.AIDS (London, England) · 2017Article
- Feline Immunodeficiency Virus Neuropathogenesis: A Model for HIV-Induced CNS Inflammation and Neurodegeneration.Veterinary sciences · 2017Review
- Emerging Role of the Cerebrospinal Fluid - Neuronal Interface in Neuropathology.Neuro : open journal · 2015Article
- Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy.Retrovirology · 2015Article
- Endocytosis of human immunodeficiency virus 1 (HIV-1) in astrocytes: a fiery path to its destination.Microbial pathogenesis · 2015Review
- HIV-1 endocytosis in astrocytes: a kiss of death or survival of the fittest?Neuroscience research · 2014Review
- Heme oxygenase-1 dysregulation in the brain: implications for HIV-associated neurocognitive disorders.Current HIV research · 2014Review
- Genotypic and phenotypic heterogeneity in the U3R region of HIV type 1 subtype C.AIDS research and human retroviruses · 2014Article
- Permissive and protective factors associated with presence, level, and longitudinal pattern of cervicovaginal HIV shedding.Journal of acquired immune deficiency syndromes (1999) · 2012Article
- HIV RNA suppression and immune restoration: can we do better?Clinical & developmental immunology · 2012Review
- HIV reservoirs in vivo and new strategies for possible eradication of HIV from the reservoir sites.HIV/AIDS (Auckland, N.Z.) · 2010Article
- The role of host genetics in the susceptibility for HIV-associated neurocognitive disorders.AIDS and behavior · 2009Review
- Cellular reservoirs of HIV-1 and their role in viral persistence.Current HIV research · 2008Review
- Comparative study of methods for detecting sequence compartmentalization in human immunodeficiency virus type 1.Journal of virology · 2007Article
- Feline immunodeficiency virus neuropathogenesis: from cats to calcium.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2007Review
- Evidence for BAG3 modulation of HIV-1 gene transcription.Journal of cellular physiology · 2007Article
- Cerebrospinal fluid is an efficient route for establishing brain infection with feline immunodeficiency virus and transfering infectious virus to the periphery.Journal of neurovirology · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
HIV-1 replicates in monocyte-derived cells in multiple organ systems; in the central nervous system, productive infection is confined to monocyte lineage cells in the brain. In addition, productive viral infection takes place in the choroid plexus, where the incidence of infection is actually higher than in brain and is present prior to the onset of AIDS and immunosuppression. Restricted or latent infection occurs in astrocytes and neurons. The presence of perineuronal CD4+ lymphocytes, as well as activated microglia, support the potential for a trans-receptor mechanism of viral entry whereas intrinsic gene profiles do not appear to participate in conferring selective neuronal vulnerability or resistance to infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.