ReviewBreast cancer research : BCR2004
Wnt signalling via the epidermal growth factor receptor: a role in breast cancer?
Review in Breast cancer research : BCR, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload.Cell death & disease · 2021Article
- The interaction of Wnt signaling members with growth factors in cultured granulosa cells.Animal reproduction · 2020Article
- GPNMB augments Wnt-1 mediated breast tumor initiation and growth by enhancing PI3K/AKT/mTOR pathway signaling and β-catenin activity.Oncogene · 2019Article
- Genomic Correlates of Exceptional Response to ErbB3 Inhibition in Head and Neck Squamous Cell Carcinoma.JCO precision oncology · 2019Article
- microRNA-219-5p inhibits epithelial-mesenchymal transition and metastasis of colorectal cancer by targeting lymphoid enhancer-binding factor 1.Cancer science · 2017Article
- Kallistatin suppresses cancer development by multi-factorial actions.Critical reviews in oncology/hematology · 2017Review
- Association among the expression of β-catenin, cyclin D1 and estrogen receptor-β in human breast cancer.Experimental and therapeutic medicine · 2015Article
- Kallistatin antagonizes Wnt/β-catenin signaling and cancer cell motility via binding to low-density lipoprotein receptor-related protein 6.Molecular and cellular biochemistry · 2013Article
- EBP50 inhibits EGF-induced breast cancer cell proliferation by blocking EGFR phosphorylation.Amino acids · 2012Article
- Mechanism of β-catenin-mediated transcriptional regulation of epidermal growth factor receptor expression in glycogen synthase kinase 3 β-inactivated prostate cancer cells.The Journal of biological chemistry · 2012Article
- Convergence between Wnt-β-catenin and EGFR signaling in cancer.Molecular cancer · 2010Review
- Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea.Journal of cell science · 2010Article
- Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth.Cancer gene therapy · 2009Article
- Transcriptome analysis identifies pathways associated with enhanced maternal performance in QSi5 mice.BMC genomics · 2008Article
- The gene expression profile induced by Wnt 3a in NIH 3T3 fibroblasts.Journal of cell communication and signaling · 2007Article
- Review
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1 author.
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Abstract
Recent data have suggested the epidermal-growth-factor receptor (EGFR) as a point of convergence for several different classes of receptor. Civenni and colleagues have now demonstrated crosstalk between Wnt signalling and the EGFR, showing that in breast epithelial cells Wnts activate downstream targets of the EGFR, including cyclin D1. Given the role of members of these pathways in the aetiology of breast cancer and as markers of outcome and potential therapeutic targets in breast cancer, this observation has a number of potential implications important for both the basic biology of breast cancer and the clinical management of the disease.
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