Evidence map›Paper›PMID 14976417›Full record

ArticleVirus genes2004

Molecular characterization of duck hepatitis B virus isolates from South African ducks.

Nomathibane P Mangisa, Heidi E Smuts, Anna Kramvis, C Wendy Linley, Michelle Skelton, Timothy J Tucker, Pauline De La M Hall, Del Kahn, Allison R Jilbert, Michael C Kew

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Article in Virus genes, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Genetic characterization of duck hepatitis B viruses from Anhui Province, China.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Molecular characterization of duck hepatitis B virus isolated from Hubei brown ducks.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2006
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Nomathibane P MangisaMRC/CANSA/University Molecular Hepatology Research Unit and Department of Medicine, University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa.
Heidi E Smuts
Anna Kramvis
C Wendy Linley
Michelle Skelton
Timothy J Tucker
Pauline De La M Hall
Del Kahn
Allison R Jilbert
Michael C Kew
University of Cape Town · ZACancer Association of South Africa · ZAUniversity of the Witwatersrand · ZASouth African Medical Research Council · ZASouth Australia Pathology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of the study was to characterize the genome of duck hepatitis B virus (DHBV) isolates from South African Pekin ducks. Duck serum and liver samples were collected from two commercial duck farms from geographically distinct regions of South Africa. In total, 498 duck serum samples were tested for the presence of DHBV DNA using either sub-genomic or full-length polymerase chain reaction (PCR) assays. The overall prevalence of DHBV infection in South African ducks was 47%. In addition, 30% of 59 liver tissues tested were DHBV DNA-positive. Six randomly selected serum or liver samples were used to clone and sequence the genomes of the South African DHBV strains. All six isolates had DHBV genomes of 3,021 nucleotides with three characteristic overlapping reading frames encoding the polymerase, surface and core gene products. No X-like gene with a traditional start codon was found. Following phylogenetic analysis, the South African DHBV isolates clustered with DHBV isolates from other "Western" countries, including United States of America, Canada, Germany and India. On translation of the open reading frames, the South African isolates were found to share signature amino acids in the polymerase and surface genes with the "Western" country isolates as opposed to those of Chinese DHBV isolates.

Indexed as

AnimalsBase SequenceCloning, MolecularDNA, ViralDucksHepadnaviridae InfectionsHepatitis B Virus, DuckHepatitis, Viral, AnimalNucleic Acid ConformationPhylogenyPoultry DiseasesRNA, ViralSouth AfricaDNA, ViralRNA, Viral

Identifiers

PMID14976417
OpenAlexW2078144665

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.