ArticleBMC genetics2003
Genome-wide screen for heavy alcohol consumption.
Article in BMC genetics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.Chinese medical journal · 2012Article
- A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models.Addiction biology · 2010Review
- Linkage analysis of alcohol dependence symptoms in the community.Alcoholism, clinical and experimental research · 2010Article
- Can we identify genes for alcohol consumption in samples ascertained for heterogeneous purposes?Alcoholism, clinical and experimental research · 2009Article
- Genome-wide linkage scan for nicotine dependence in European Americans and its converging results with African Americans in the Mid-South Tobacco Family sample.Molecular psychiatry · 2008Article
- Candidate genes, pathways and mechanisms for alcoholism: an expanded convergent functional genomics approach.The pharmacogenomics journal · 2007Article
- Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster.Genome biology · 2007Article
- Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2.BMC genetics · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundTo find specific genes predisposing to heavy alcohol consumption (self-reported consumption of 24 grams or more of alcohol per day among men and 12 grams or more among women), we studied 330 families collected by the Framingham Heart Study made available to participants in the Genetic Analysis Workshop 13 (GAW13).
resultsParametric and nonparametric methods of linkage analysis were used. No significant evidence of linkage was found; however, weak signals were identified in several chromosomal regions, including 1p22, 4q12, 4q25, and 11q24, which are in the vicinity of those reported in other similar studies.
conclusionOur study did not reveal significant evidence of linkage to heavy alcohol use; however, we found weak confirmation of studies carried out in other populations.
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